摘要
目的探讨缺血性脑卒中合并代谢综合征的危险因素,并建立风险评估模型。方法将缺血性脑卒中患者450例分为代谢综合征组268例和非代谢综合征组182例,比较两组临床特点。结果两组的体质指数、饮酒史、收缩压、空腹血糖、糖化血红蛋白、高密度脂蛋白胆固醇、总胆固醇、甘油三酯的组间差异有统计学意义(P<0.05),而年龄、性别、臀腰比、吸烟史、NIHSS评分、舒张压、低密度脂蛋白胆固醇的组间差异无统计学意义(P>0.05)。Logistic回归分析显示,经常饮酒、糖化血红蛋白、收缩压、甘油三酯、高密度脂蛋白胆固醇为重要影响因素。代谢综合征组的病死率和并发症的发生率均高于非代谢综合征组。结论肥胖、饮酒、高血压、高血糖、高血脂均为缺血性脑卒中合并代谢综合征的危险因素,影响患者病情发展,临床应采取针对性预防措施。
Objective To investigate the risk factors of an ischemic stroke complicated with metabolic syndrome and to establish a risk assessment model. Methods 450 patients with ischemic stroke were divided into the metabolic syndrome group(n=268)and non-metabolic syndrome group(n=182).The clinical characteristics of the two groups were compared. Results The difference of BMI, drinking history, SBP, FBG, HbA1c, HDL-C, TC,and TG in the two groups were statistically significant(P<0.05), but there was no significant difference in age, gender, hip to waist ratio, smoking history,NIHSS score, DBP, LDL-C, etc.(P>0.05). Logistic regression analysis showed that frequent drinking, HbA1c, SBP, TG, HDL-C were the more important influencing factors, and the rate of mortality and the incidence of other complications in patients with metabolic syndrome were higher than those without metabolic syndrome. Conclusion Obesity, drinking, hypertension, hyperglycemia, and hyperlipidemia are the risk factors of an ischemic stroke complicated with metabolic syndrome, which affect the development of the disease. Therefore, clinical targeted preventive measures should be undergone.
作者
滕秋玉
TENG Qiu-yu(Shenyang Red Cross Hospital,Shenyang,Liaoning,110000,China)
出处
《中国冶金工业医学杂志》
2020年第6期627-629,共3页
Chinese Medical Journal of Metallurgical industry
基金
辽宁省科学技术厅计划项目(20180550374)。
