摘要
目的:分析雌激素联合甲硝唑用于萎缩性阴道炎治疗疗效及不良反应率。方法:抽取于2017年10月~2018年12月某院收治的90例萎缩性阴道炎患者开展本次研究,随机将其分为对照组和治疗组各45例。对照组用甲硝唑治疗,治疗组用雌激素联合甲硝唑治疗,对比临床观察指标、治疗总有效率、不良反应发生率。结果:子宫内膜厚度、阴道pH值与对照组相比,治疗组较低,而表层细胞百分比治疗组较高(P<0.05);治疗总有效率与对照组相比,治疗组较高(P<0.05);不良反应两组相比,无显著差异(P>0.05)。结论:雌激素联合甲硝唑用于萎缩性阴道炎治疗中,临床疗效显著,不仅可以改善子宫内膜厚度、阴道pH值,还可以提高治疗效果,且不良反应经有效处理后可缓解,安全性高,值得推广。
Objective:To analyze the efficacy and adverse reaction rate of estrogen combined with metronidazole in the treatment of atrophic vaginitis.Methods:90 patients with atrophic vaginitis admitted to a hospital from October 2017 to December 2018 were selected for this study.They were randomly divided into the control group and the treatment group,with 45 cases in each group.The control group was treated with metronidazole,while the treatment group was treated with estrogen combined with metronidazole,then the clinical observation indexes,total effective rate and adverse reaction rate were compared.Results:Compared with the control group,endometrial thickness and vaginal PH value were lower in the treatment group,while the percentage of surface cells was higher in the treatment group(P<0.05).The total effective rate was higher in the treatment group than in the control group(P<0.05).There was no significant difference between the two groups in the incidence of adverse reactions(P<0.05).Conclusion:Estrogen combined with metronidazole in the treatment of atrophic vaginitis has significant clinical effect,which can not only improve the endometrium thickness and vagina pH value,but also improve the treatment effect and alleviate adverse reactions after effective treatment,with high safety,and is worthy of promotion.
作者
周小改
Zhou Xiaogai(Jutan Hospital,Neixiang County,Henan Province,Nanyang 474350)
出处
《数理医药学杂志》
2021年第1期127-128,共2页
Journal of Mathematical Medicine
关键词
萎缩性阴道炎
雌激素
甲硝唑
治疗效果
不良反应发生率
atrophic vaginitis
estrogen
metronidazole
therapeutic effect
incidence of adverse reactions
