摘要
目的:探究任顺平教授治疗功能性消化不良脾虚气滞证的用药规律,为临床防治及新药研发提供参考。方法:收集任顺平教授治疗功能性消化不良脾虚气滞证的首诊有效中药处方144首,录入至中医传承辅助平台(V2.5)系统,利用系统中的关联规则以及无监督熵聚类算法等数据分析方法进行数据挖掘。结果:144首中药处方中,涉及中药56味,其中,以温性、寒性,辛苦甘味药的使用较多,且其多入脾胃肺大肠及肝胆经;基于关联规则分析,得到1首核心处方:藿香、紫苏梗、柴胡、黄芩、姜半夏、党参、厚朴、陈皮、白术、枳实、木香、砂仁、旋复花、生姜、神曲、炒谷芽、炒麦芽;基于无监督熵聚类算法,得到17条核心中药组合及2个潜在的新方组合。结论:任顺平教授治疗功能性消化不良脾虚气滞证,善从“通降”入手,采用健脾、疏肝、降胃、宣肺、通腑“五位一体”整体辨治,且用药轻灵,性味醇和。同时,注重证-症结合,灵活化裁。
Objective To explore the medication rules of Professor REN Shun-ping’s prescription for treating spleen deficiency and qi stagnationsyndrometype of functional dyspepsia,so as to provide reference for clinical prevention and development of new drugs.MethodsThe 144 Chinese herbal formulas considered as active prescribed by professor REN Shun-ping for patients with spleen deficiency and qi stagnation syndrometype of functional dyspepsiawho visited for the first time were collected,and entered into TCM inheritance auxiliary platform(V2.5),and then mined by some data mining methodsof the software,such as the association rulesand unsupervised entropy hierarchical clustering.ResultsThis study involved 144 Chinese herbal formulas,including a total of 56 Chinese herbs.Of these Chinese herbs,the herbs of cold and warm nature,and pungent,bitterand sweet in flavors were used in a quite high frequency,all of which act onspleen,stomach,lungs,large intestine,liverand gallbladder meridians.Based on the association rules analysis results,a core Chinese herbal formula was summarized which is composed of patchouli,perilla stem,radix bupleuri,scutellaria,ginger pinellia,codonopsispilosula,magnolia bark,tangerine peel,large-headed atractylodes,immature bitter orange,wood incense,fructusamomi,inulabritannicachinensis,ginger,medicated leaven,fried rice and fried malt.And a total of 17 groups of core herbs and 2 groups of new Chinese herbswere discovered based on unsupervised entropy hierarchical clustering.Conclusions In treating spleen deficiency and qi stagnation syndrometype of functional dyspepsia,professor Renmainly treats spleen deficiency and qi stagnation syndrometype of functional dyspepsia from the perspective of"tongjiang",using the"five-in-one"strategy of strengthening the spleen,evacuating the liver,coming down qi from the stomach,dispersing lung,and bowel-reflexing to treat patients as a whole.And dosage of prescribedherbsare light,herb nature is mild.Atthe same time,heprescribeswith great diversity based on comprehensi
作者
刘岩波
王忻彤
任顺平
LIU Yan-bo;WANG Xin-tong;REN Shun-ping(Shanxi University of Traditional Chinese Medicine,Taiyuan 030024,China;Affiliated Hospital of Shanxi University of Traditional Chinese Medicine,Taiyuan 030024,China)
出处
《海南医学院学报》
CAS
2020年第24期1897-1902,共6页
Journal of Hainan Medical University
基金
国家中医药管理局2014年中医药行业科研专项(201407001-12)
山西省重点研发计划项目(201703D321020)。
关键词
中医传承辅助平台
功能性消化不良
脾虚气滞证
任顺平
用药规律
TCM inheritance support platfom
Functional dyspepsia
Spleen deficiency and qistagnationtype syndrome
Ren Shun-ping
Rule of prescription
