摘要
目的观察柴胡桂枝龙骨牡蛎汤加味治疗围绝经期焦虑性失眠的效果。方法选取本院接诊的300例围绝经期女性焦虑性失眠患者作为研究对象,按照随机数表法将其分为研究组和对照组,每组150例。对照组采用常规治疗,研究组采用柴胡桂枝龙骨牡蛎汤加味治疗。比较2组治疗前后绝经综合征症状评定量表(Kupperman)评分、中医证候评分、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、匹兹堡睡眠质量指数(PSQI)评分及治疗效果,并记录2组的入睡时间和睡眠时间。结果研究组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,2组Kupperman评分、中医症候评分、SAS、SDS指标数值均下降,且研究组以上指标均低于对照组,差异有统计学意义(P<0.05)。治疗前,2组PSQI评分、入睡时间、睡眠时间比较,差异无统计学意义(P>0.05);治疗后,研究组PSQI评分低于对照组,入睡时间短于对照组,睡眠时间长于对照组,差异均有统计学意义(P<0.05)。结论柴胡桂枝龙骨牡蛎汤加味治疗围绝经期女性焦虑性失眠的效果显著,可有效改善睡眠质量和抑郁、焦虑情绪,缩短入睡时间,延长睡眠时间。
Objective To observe effect of supplemented Chaihu Guizhi Longgu Muli Decoction in treatment of insomnia induced by anxiety in perimenopausal period.Methods A total of 300 female perimenopausal patients with insomnia induced by anxiety were selected as research objects.According to random number table method,they were divided into study group and control group,with 150 cases in each group.The control group was given conventional treatment,and the study group was treated with supplemented Chaihu Guizhi Longgu Muli Decoction.Kupperman Menopausal Index(Kupperman)score,traditional Chinese medicine symptom score,Self-rating Anxiety Scale(SAS)score,Self-rating Depression Scale(SDS)score,Pittsburgh Sleep Quality Index(PSQI)score,falling asleep time,sleep duration before and after treatment as well as treatment effect were compared and recorded.Results The total effective rate of the study group was significantly higher than that of the control group(P<0.05).After treatment,Kupperman score,traditional Chinese medicine symptom,SAS and SDS scores of the two groups were significantly declined,and were significantly lower in study group than those of the control group(P<0.05).Before treatment,there were no significant differences in PSQI score,falling asleep time,sleep duration between the two groups(P>0.05).After treatment,the PSQI score was lower,and falling asleep time was significantly shorter,and sleep time was significantly longer than that of the control group(P<0.05).Conclusion Chaihu Guizhi Longgu Muli Decoction has a remarkable effect in perimenopausal women with anxiety induced insomnia,which can effectively improve the sleep quality,depression and anxiety,shorten the falling asleep time and prolong sleep duration.
作者
卫坚
杨向利
WEI Jian;YANG Xiangli(Geriatrics Department,Pucheng County Hospitalin Weinan City of Shaanxi Province,Weinan,Shaanxi,715500;Pharmacy Department,Pucheng County Hospital in Weinan City of Shaanxi Province,Weinan,Shaanxi,715500)
出处
《实用临床医药杂志》
CAS
2020年第21期43-45,49,共4页
Journal of Clinical Medicine in Practice
基金
陕西省渭南市卫健委计划项目(2020PSL029)。
关键词
焦虑性失眠
柴胡桂枝龙骨牡蛎汤
中医证候
匹兹堡睡眠质量指数
绝经综合征症状评定量表
焦虑自评量表
抑郁自评量表
anxiety induced insomnia
Chaihu Guizhi Longgu Muli Decoction
traditional Chinese medicine symptom score
Pittsburgh Sleep Quality Index
Kupperman Menopausal Index
Self-rating Anxiety Scale
Self-rating Depression Scale
