摘要
目的探讨奥卡西平(OXC)与卡马西平(CBZ)对前庭阵发症(VP)患者眩晕症状、生活质量的影响。方法将56例VP患者随机分为对照组及观察组,各28例,对照组采用CBZ治疗,观察组采用OXC治疗,比较两组的治疗效果。结果治疗后,观察组的眩晕发作频率、眩晕程度、DHI评分均优于对照组,不良反应总发生率低于对照组(P<0.05)。结论OXC和CBZ治疗VP的效果相当,但OXC对眩晕症状、生活质量的改善效果较明显,且不良反应较少。
Objective To explore the effects of oxcarbazepine(OXC)and carbamazepine(CBZ)on vertigo symptoms and quality of life in patients with vestibular paroxysmia(VP).Methods A total of 56 patients with VP were randomly divided into control group and observation group,with 28 cases in each group.The control group was treated with CBZ,and the observation group was treated with OXC.The treatment effects of the two groups were compared.Results After treatment,the frequency of dizziness,the degree of dizziness and the DHI scores of the observation group were better than those of the control group,and the total incidence of adverse reactions was lower than that of the control group(P<0.05).Conclusion The OXC and CBZ in the treatment of VP have similar effect,but OXC has more obvious improvement effects on the vertigo symptoms and quality of life,and has fewer adverse reactions.
作者
常虎飞
郝军
CHANG Hufei;HAO Jun(Yulin No.2 Hospital,Yulin 719000,China)
出处
《临床医学研究与实践》
2020年第35期69-70,共2页
Clinical Research and Practice
关键词
前庭阵发症
奥卡西平
卡马西平
vestibular paroxysmia
oxcarbazepine
carbamazepine