摘要
目的探讨不同性别中老年人各腰椎体脂肪含量(fat fraction,FF)、R2*与骨密度(bone mineral density,BMD)的相关性。材料与方法通过MRI脂肪定量技术测量40例中老年人(男女各20例)共200个腰椎体的FF、R2*值,通过定量CT (quantitative computedtomography,QCT)测量腰椎各椎体BMD,采用SNK检验比较不同性别腰椎各椎体BMD、FF和R2*值,两独立样本t检验比较不同性别间腰椎BMD、FF和R2*值。Spearman相关分析不同性别腰椎各椎体FF、R2*值与BMD的相关性。结果不同性别中老年人L1-L5各椎体间BMD、R2*比较,差异均无明显统计学意义(P>0.05),各椎体间FF比较,差异均有统计学意义(P<0.05),其中男、女性中老年人L4FF、L5FF均大于L1FF,男性L4FF大于L2FF。男、女两组腰椎体BMD、FF比较,差异无明显统计学意义(P>0.05),R2*比较差异具有统计学意义(P<0.05),且男性腰椎体R2*大于女性。不同性别中老年人腰椎BMD与FF值均呈负相关(rs男=-0.76,rs女=-0.77,P均<0.05),与R2*值均呈正相关(rs男=0.56,rs女=0.45,P均<0.05)。结论中老年人腰椎体BMD与FF、R2*值有一定相关性,且中老年女性R2*小于男性,同时中老年人下腰椎FF值较上腰椎高。
Objective:To investigate the correlation between fat fraction(FF),R2*and bone mineral density(BMD)of lumbar vertebrae in middle-aged and elderly people of different genders.Materials and Methods:The FF and R2*values of each lumbar vertebra were measured by MRI fat quantitative technique(mDIXON-Quant),and quantitative computed tomography(QCT)was used to measure the BMD of each lumbar vertebra in 40 middleaged and elderly patients(20 males and 20 females).The BMD,FF and R2*values of various lumbar vertebrae of different genders were compared by SNK test.The BMD,FF and R2*values of lumbar vertebrae of different genders were compared by t test.Pearson correlation analysis was conducted to analyze the correlation between FF and R2*values with BMD of each lumbar vertebrae of different genders.Results:The BMD and R2*value of each vertebral body between the middle-aged and elderly people in different genders showed no statistically significant difference(P>0.05).There were statistically significant differences in FF value of each vertebral body between the middle-aged and elderly people in different genders(P<0.05).The values of L4 FF and L5 FF were greater than L1 FF in both male and female groups,and the value of L4 FF in male group was greater than L2 FF.There was no statistically significant difference in BMD and FF between male and female groups(P>0.05).There was statistically significant difference in R2*between male and female groups(P<0.05),and R2*in male group was greater than that in female group.The BMD and FF values of the lumbar spine in the middle-aged and elderly people of different genders were negatively correlated(rmale=-0.76,rfemale=-0.77,P<0.05),and were positively correlated with R2*value(rmale=0.56,rfemale=0.45,P<0.05).Conclusions:There was a certain correlation between lumbar body BMD with FF and R2*values in middle-aged and elderly people,and R2*values in middle-aged and elderly women were lower than those in men.Besides,the FF values in lower lumbar spine were higher than those in upper lumbar sp
作者
马培旗
袁玉山
彭彬
张宗夕
张磊
张杨
张小艳
王仲秋
MA Peiqi;YUAN Yushan;PENG Bin;ZHANG Zongxi;ZHANG Lei;ZHANG Yang;ZHANG Xiaoyan;WANG Zhongqiu(Department of Medical Imaging,Fuyang People’s Hospital,Fuyang 236000,China)
出处
《磁共振成像》
CAS
2020年第12期1186-1189,共4页
Chinese Journal of Magnetic Resonance Imaging
关键词
磁共振成像
定量CT
骨密度
脂肪分数
R2*
magnetic resonance imaging
quantitative computed tomography
bone mineral density
fat fraction
R2*
