摘要
目的探讨重型颅脑外伤合并肺部感染患者系列临床表现并观察采用盐酸氨溴索药物治疗后获得临床效果。方法方便选取该院2017年6月—2019年12月收治的40例重型颅脑外伤合并肺部感染患者,按照数字奇偶法分组;治疗组(20例):采用小剂量盐酸氨溴索药物展开合并症治疗;对照组(20例):采用大剂量盐酸氨溴索药物展开合并症治疗;就组间合并症疗效数据、咳嗽咳痰比例、发热比例、肺部干湿啰音比例、白细胞增高比例、其他比例以及总不良反应率展开对比。结果治疗组重型颅脑外伤合并肺部感染患者疗效数据(90.00%)同对照组(85.00%)比较差异无统计学意义(χ~2=0.000,P>0.05);治疗组重型颅脑外伤合并肺部感染患者咳嗽咳痰比例、发热比例、肺部干湿啰音比例、白细胞增高比例、其他比例同对照组比较,差异无统计学意义(χ~2=0.125、0.107、0.125、0.000、0.000,P>0.05);治疗组重型颅脑外伤合并肺部感染患者总不良反应率(15.00%)低于对照组(45.00%),差异有统计学意义(χ~2=4.286,P<0.05)。结论对于重型颅脑外伤合并肺部感染患者而言,其表现主要集中于咳嗽咳痰、发热、肺部干湿啰音、白细胞增高等方面,治疗期间,盐酸氨溴索药物的应用可获得较为理想效果,并且小剂量应用可使得不良反应显著减轻,呈现出更高治疗安全性,最终实现重型颅脑外伤合并感染患者有效预后。
Objective To investigate the clinical manifestations of severe craniocerebral injury complicated with pulmonary infection and observe the clinical effect of ambroxol hydrochloride treatment.Methods 40 cases of severe craniocerebral injury with pulmonary infection admitted to the hospital from June 2017 to December 2019 were divided into two groups by digital parity method.Treatment group(20 cases):small dose ambroxol hydrochloride drug to start the treatment of complications;control group(20 cases):used of large dose ambroxol hydrochloride drugs to carry out the treatment of complications;comparisons were made on the efficacy data of intergroup comorbid diseases,the proportion of cough and cough phlegm,the proportion of fever,the proportion of lung dry and wet rales,the proportion of increased white blood cells,other proportion and the rate of total adverse reactions.Results The therapeutic data of patients with severe craniocerebral injury complicated with pulmonary infection in the treatment group(90.00%)were not significantly different from that of the control group(85.00%),the difference wa statistically significant(χ2=0.000,P>0.05).There was no significant difference in the proportion of cough and sputum,the proportion of fever,the proportion of dry and wet pulmonary rales,the proportion of increased white blood cells,and the other proportions of patients with severe head injury and pulmonary infection in the treatment group(χ2=0.125,0.107,0.125,0.000,0.000,P>0.05).The total adverse reaction rate of patients with severe craniocerebral injury complicated with pulmonary infection in the treatment group(15.00%)was significantly lower than that of the control group(45.00%),and the difference was statistically significant(χ2=4.286,P<0.05).Conclusion For patients with severe craniocerebral trauma with lung infection,its performance is mainly focused on cough and expectoration,fever,increased lung wet then,white blood cells,during the treatment,hydrochloric acid ammonia bromine line drug application type can obt
作者
缪舜
彭国宏
韩萍
MIAO Shun;PENG Guo-hong;HAN Ping(Department of Critical Care Medicine,Jiangyan Hospital of Traditional Chinese Medicine,Taizhou,Jiangsu Province,225500 China;Department of Neurosurgery,Jiangyan Hospital of Traditional Chinese Medicine,Taizhou,Jiangsu Province,225500 China)
出处
《中外医疗》
2020年第32期124-126,共3页
China & Foreign Medical Treatment
关键词
重型颅脑外伤
肺部感染
临床表现
盐酸氨溴索
疗效
不良反应
Severe craniocerebral injury
Pulmonary infection
Clinical manifestations
Ambroxol hydrochloride
Curative effect
Adverse reactions
