摘要
目的调查围绝经期及绝经后体检女性代谢综合征(Mets)的发病情况,了解各年龄组代谢指标的差异。方法随机抽取2019年l月至6月在华东疗养院接受健康体检的40~70岁女性共428例为研究对象,按年龄分为A组(40~45岁)81例、B组(46~50岁)82例、C组(51~55岁)76例、D组(56~60岁)79例、E组(61~65岁)71例、F组(≥66岁)39例,分析Mets的患病率及各年龄组代谢指标的差异。结果Mets总体患病率为12.38%,Mets各组分中肥胖、高血压、血糖异常、甘油三酯(TG)异常、高密度脂蛋白胆固醇(HDL-C)异常的发生率分别为18.69%、23.60%、14.95%、19.63%、3.50%,除HDL-C外,各年龄组间Mets患病率及各组份异常存在随年龄增长而增高的趋势(χ^2值分别为29.488、14.125、28.502、19.829、25.472,均P<0.05);各年龄组收缩压(SBP)、TG、总胆固醇(TC)、低密度脂蛋白(LDL-C)和尿酸(UA)比较均有统计学差异(F值分别为3.187、3.764、7.771、6.844、5.382,均P<0.05),进一步比较发现,F组SBP显著高于其他组,E、F组TG、UA显著高于其他组,C、D、E组TC、LDL-C显著高于A、B组。结论围绝经期及绝经后女性Mets患病率较高,随着年龄的增长异常代谢指标显著上升,应加强宣传教育,及早采取干预措施,提高女性的生活质量。
Objective To survey prevalence of metabolic syndrome(Mets)in perimenopausal and postmenopausal women,and to understand differences in metabolic indexes among women in different age groups.Methods A total of 428 women aged 40~70 years who received physical examination in Huadong Sanatorium from January to June 2019 were randomly selected as the study subjects.They were divided into group A(aged 40~45 years,81 cases),group B(aged 46~50 years,82 cases),group C(aged 51~55 years,76 cases),group D(aged 56~60 years,79 cases),group E(aged 61~65 years,71 cases)and group F(aged≥66 years,39 cases)respectively.The prevalence of Mets and the differences in metabolic indexes among different age groups were analyzed.Results The overall prevalence of Mets was 12.38%.The incidences of obesity,hypertension,abnormal blood glucose,abnormal triglyceride(TG)and abnormal high-density lipoprotein cholesterol(HDL-C)in Mets were 18.69%,23.60%,14.95%,19.63%and 3.50%respectively.The prevalences of Mets and all abnormal components of Mets except HDL-C increased with increase in age(χ^2=29.488,14.125,28.502,19.829 and 25.472 respectively,all P<0.05).There were significant differences in systolic blood pressure(SBP),TG,total cholesterol(TC),LDL-C and uric acid(UA)among different age groups(F=3.187,3.764,7.771,6.844 and 5.382,respectively,all P<0.05).Further comparison showed that SBP in group F was significantly higher than that in other groups,TG and UA in group E and group F were significantly higher than those in other groups,TC and LDL-C in group C,group D and group E were significantly higher than those in group A and group B.Conclusion The prevalence of Mets significantly increases with increase in age of perimenopausal and postmenopausal women.The results indicate that early intervention measures should be taken to reduce the risk of Mets and improve the quality of life of those perimenopausal and postmenopausal women.
作者
周小会
朱菊平
刘梅
谢琦
史艳丰
邵春云
王科芳
汪丽杰
ZHOU Xiaohui;ZHU Juping;LIU Mei;XIE Qi;SHI Yanfeng;SHAO Chunyun;WANG Kefang;WANG Lijie(Department of Gynecology,Huadong Sanatorium,Jiangsu Wuxi 214065,China)
出处
《中国妇幼健康研究》
2020年第11期1489-1493,共5页
Chinese Journal of Woman and Child Health Research
基金
华东疗养院院级课题(201810)。
关键词
围绝经期
代谢综合征
患病率
体检
perimenopausal
metabolic syndrome(Mets)
morbidity rate
physical examination
