摘要
目的探讨2型糖尿病女性绝经与颈动脉粥样硬化患病率的相关性。方法回顾性分析2018年1月至2020年12月于广元市第一人民医院住院的157例2型糖尿病患者的临床资料,收集患者临床资料,按照是否绝经分为绝经患者(n=115)与未绝经患者(n=42);再经彩色多普勒超声分为颈动脉粥样硬化患者(n=64)与无颈动脉粥样硬化患者(n=93)。采用多因素Logistic回归分析2型糖尿病女性绝经的影响因素。结果颈动脉粥样硬化患者与无颈动脉粥样硬化患者游离三碘甲状腺原氨酸(FT_(3))、游离甲状腺素(FT_(4))、促甲状腺素(TSH)、比较差异无统计学意义。单因素分析结果显示,年龄、收缩压(SBP)、颈动脉粥样硬化均为2型糖尿病女性绝经的影响因素,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,年龄是2型糖尿病女性绝经的独立危险因素(OR>1,P<0.05)。结论2型糖尿病女性绝经与颈动脉粥样硬化患病率无相关性,可能因研究资料较少导致,应定期检查有无颈动脉粥样硬化,进一步深入研究。
Objective To investigate the correlation between menopause and the prevalence of carotid atherosclerosis in women with type 2 diabetes.Methods The clinical data of 157 patients with type 2 diabetes who were hospitalized in Guangyuan First People's Hospital from January 2018 to December 2020 were retrospectively analyzed.The clinical data of patients were collected and divided into menopausal patients(n=115)and premenopausal patients(n=42)according to whether they were menopausal or not;they were divided into carotid atherosclerosis patients(n=64)and non-carotid atherosclerosis patients(n=93)by color Doppler ultrasound.Multivariate Logistic regression analysis was used to analyze the influencing factors of menopause in women with type 2 diabetes.Results There was no significant difference in free triiodothyronine(FT_(3)),free thyroxine(FT_(4))and thyroid stimulating hormone(TSH)between patients with carotid atherosclerosis and those without carotid atherosclerosis.The results of univariate analysis showed that age,systolic blood pressure(SBP)and carotid atherosclerosis were the influencing factors of menopause in women with type 2 diabetes,and the difference was statistically significant(P<0.05).Multivariate Logistic regression analysis showed that age was an independent risk factor for menopause in women with type 2 diabetes(OR>1,P<0.05).Conclusion There is no correlation between menopause and the prevalence of carotid atherosclerosis in women with type 2 diabetes,which may be caused by less research data.Regular examination of carotid atherosclerosis should be carried out for further study.
作者
张玲
陈驰
曾慧
梁元碧
ZHANG Ling;CHEN Chi;ZENG Hui;LIANG Yuanbi(Department of Endocrinology,Guangyuan First People's Hospital,Guangyuan,Sichuan,628000,China)
出处
《当代医学》
2023年第29期159-162,共4页
Contemporary Medicine
关键词
2型糖尿病
绝经
颈动脉粥样硬化
Type 2 diabetes mellitus
Menopause
Carotid atherosclerosis
