摘要
目的:回顾性分析清肺排毒汤在普通型/重型新型冠状病毒肺炎患者中的使用情况及疗效。方法:收集武汉市第三医院使用过清肺排毒汤的已出院病例108例,分析其在普通型、重型患者中使用分布情况,2组用药前后临床症状、检测指标的检测结果对比以及对舌苔辨证的影响,早期使用清肺排毒汤对患者康复时间、复阳的影响。结果:普通型患者年龄中位数为61岁,重型患者为69岁,差异有统计学意义(P<0.05),普通型与重型患者共同的出现频率较高的临床症状为发热、咳嗽(干咳)、胸闷气促。经过治疗后,体温恢复正常,其余症状均得到改善。临床症状痊愈率普通型为97.6%,重型为73.1%。84.1%的普通型病例以及53.8%的重型病例中性粒细胞百分比值、淋巴细胞百分比值、C反应蛋白恢复正常值。所有病例中,入院3 d内即开始用药的病例在院时间明显少于入院7 d及以上才用药的病例(P<0.05)。在重型新冠肺炎病例中,入院6 d内首次用药的病例在院天数明显少于入院7 d及以上才用药的病例(P<0.05)。结论:清肺排毒汤在普通型及重型新型冠状病毒患者中有一定临床疗效,且早期干预能缩短患者住院时间,防止患者病情加重。
OBJECTIVE To retrospectively analyze the use and efficacy of Qingfei Paidu decoction in patients with common/severe novel coronavirus pneumonia.METHODS 108 discharged patients who had used Qingfei Paidu decoction in a hospital were collected.The distribution of Qingfei Paidu decoction in common and severe patients was analyzed.The clinical symptoms,detection indicators before and after treatment and the effect on tongue coating syndrome differentiation were compared between the two groups.The effect of early use of Qingfei Paidu decoction on the rehabilitation time and recovery of patients was analyzed.RESULTS The median age of patients was 61 years in common type and 69 years in severe type,with significant difference(P<0.05).The common clinical symptoms of patients with common type and severe type were fever,cough(dry cough),chest distress and shortness of breath.After treatment,the body temperature returned to normal,and the other symptoms were improved.The recovery rate of clinical symptoms was 97.6%in common type and 73.1%in severe type.Neutrophil percentage values,lymphocyte percentage values,and C-reactive protein returned to normal values in 84.1%of usual cases as well as in 53.8%of severe cases.In all cases,the in-hospital time of patients who started medication within 3 days after admission was significantly shorter than that of patients who did not start medication until 7 days or more after admission(P<0.05).In patients with severe coronary pneumonia,the number of days of hospitalization was significantly less in patients who took the first medication within 6 days of admission than in those who took the drug 7 days or more after admission(P<0.05).CONCLUSION Qingfei Paidu decoction had certain clinical efficiency both in ordinary type and severe type coronavirus disease.Early intervention can promote the recovery of patients,reduce the number of hospitalization days,and prevent the aggravation of the disease.
作者
孟军华
何阳
陈茜
高强
陈永刚
安靖
MENG Jun-hua;HE Yang;CHEN Qian;GAO Qiang;CHEN Yong-gang;AN Jing(Department of Pharmacy,The Third Hospital of Wuhan,Tongren Hospital of Wuhan University,Hubei Wuhan 430060,China;Department of Traditional Chinese Medicine,The Third Hospital of Wuhan,Tongren Hospital of Wuhan University,Hubei Wuhan 430060,China)
出处
《中国医院药学杂志》
CAS
北大核心
2020年第20期2152-2157,共6页
Chinese Journal of Hospital Pharmacy
关键词
清肺排毒汤
新型冠状病毒
普通型
重型
回顾性研究
Qingfei Paidu decoction
COVID-19
type common
type severe
retrospective study
