摘要
目的:比较大、中、小粒平贝母止咳、祛痰、抗炎功效,探讨采用大小作为平贝母药材质量评价标准的科学性。方法:采用小鼠氨水引咳法比较不同大小平贝母的止咳作用;采用小鼠气管段酚红排痰法比较祛痰作用;采用小鼠耳廓肿胀法比较抗炎作用。结果:止咳作用中贝母有优于小贝母的趋势;祛痰作用三者效果接近;抗炎作用中贝母有优于小贝母的趋势,但差异均无统计学意义。结论:以平贝母的大小评价药材质量缺乏科学依据。
Objective:To investigate the rationality of evaluation the quality of the Fritillariae Ussuriensis Bulbus by the size of the bulbs based on the cough,expectorant and anti-inflammatory effects.Methods:The antitussive effect was tested by ammonium hydroxide causing cough method in mice,the sputum effect was observed by tracheal phenol red shedding method in mice,the anti-inflammatory effects was measured by mice ear swelling mehtod.Results:In terms of antitussive,the medium size Fritillariae Ussuriensis Bulbus seemed to show better effect than small size one.In terms of expectoration,they had all similar effect.In terms of anti-inflammatory,the medium size one seeded to show better effect than the small size one.Although there existed a trend,there was no statistical difference.Conclusion:There is no scientific basis for using small size as an index to evaluate the quality of Fritillariae Ussuriensis Bulbus.
作者
赵倩
李波
沈莹
孟祥才
ZHAO Qian;LI Bo;SHEN Ying;MENG Xiang-cai(Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《中国现代中药》
CAS
2020年第9期1475-1477,1484,共4页
Modern Chinese Medicine
基金
2018年中医药公共卫生服务补助专项(财社[2018]43号)。
关键词
平贝母
止咳
祛痰
抗炎
质量评价
Fritillariae Ussuriensis Bulbus
antitussive effect
expectorant effect
anti-inflammatory effects
quality evaluation
