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持续皮下注射与多次皮下注射胰岛素治疗小儿糖尿病的临床疗效 被引量:8

The Clinical Effects of Continuous Subcutaneous Injection and Multiple Subcutaneous Injections of Insulin in the Treatment of Infantile Diabetes
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摘要 目的研究持续皮下注射与多次皮下注射胰岛素治疗小儿糖尿病的临床效果。方法抽取该院2017年1月—2020年1月收治的22例糖尿病患儿为该次研究对象,入院时根据不同治疗措施,将全部患儿分为对照组(n=11)和观察组(n=11)两组,对照组患儿给予多次皮下注射胰岛素治疗,观察组患儿则给予持续皮下注射胰岛素治疗,对两组患儿情况进行比较。结果观察组患儿糖化血红蛋白、餐后2 h血糖和空腹血糖均优于对照组,组间数据差异有统计学意义(P<0.05);观察组低密度脂蛋白胆固醇、高密度脂蛋白胆固醇和三酰甘油水平则明显优于对照组,且观察组血糖达标、尿酮消失时间和低血糖率也明显优于对照组,组间数据差异有统计学意义(P<0.05)。结论对小儿糖尿病采取持续皮下注射胰岛素治疗,其疗效相对于多次皮下注射更好,有助于改善血脂、血糖水平,减少低血糖症状,对于患儿疾病预后具有积极作用。 Objective To study the clinical effects of continuous subcutaneous injection and multiple subcutaneous injections of insulin in the treatment of children with diabetes. Methods The 22 children with diabetes who were admitted to the hospital from January 2017 to January 2020 were selected as the subjects of this study. Upon admission, according to different treatment measures, all children were divided into control group(n=11) and observation group(n=11), children in the control group were given multiple subcutaneous injections of insulin, and children in the observation group were given continuous subcutaneous injections of insulin. The conditions of the two groups were compared. Results The glycated hemoglobin, 2 h postprandial blood glucose and fasting blood glucose of the observation group were better than those of the control group. The difference was statistically significant(P <0.05);the observation group had low density lipoprotein cholesterol and high density lipoprotein cholesterol and triacylglycerol levels were significantly better than those of the control group, and the observation group’s blood glucose standard, urine ketone disappearance time and hypoglycemia rate were also significantly better than those of the control group. The difference was statistically significant(P<0.05). Conclusion Continuous subcutaneous injection of insulin for children with diabetes has a better effect than multiple subcutaneous injections. It can help improve blood lipids and blood glucose levels, reduce symptoms of hypoglycemia, and has a positive effect on the prognosis of children with disease.
作者 郑庆锋 ZHENG Qing-feng(Zhengxing Hospital of Zhangzhou,Zhangzhou,Fujian Province,363000 China)
出处 《糖尿病新世界》 2020年第18期56-58,共3页 Diabetes New World Magazine
关键词 持续皮下注射 小儿糖尿病 多次皮下注射 胰岛素治疗 Continuous subcutaneous injection Pediatric diabetes Multiple subcutaneous injections Insulin therapy
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