摘要
目的探讨急性脑梗死患者发生认知功能障碍的危险因素及预防办法。方法对本院2017年5月至2019年5月收治的239例急性脑梗死患者使用简易精神状态量表进行评估,根据患者是否存在认知功能障碍分为认知障碍组(n=55)、无认知障碍组(n=184);实施单因素和多因素分析急性脑梗死患者认知功能障碍的危险因素。结果急性脑梗死患者认知功能障碍的发生率是23.01%(55/239)。多因素Logistic回归分析结果显示,年龄、糖尿病史、脑卒中史、脑血管疾病史、高血压史、NIHSS评分>10分、合并多发性脑梗死、合并左侧半球脑梗死以及颈动脉斑块是急性脑梗死后认知障碍的相关危险因素(P<0.05)。对两组患者积极治疗与康复训练,两组患者Barthel评分有所提升,治疗3个月后评分明显高于治疗1个月时(P<0.05);治疗1个月、治疗3个月时,非认知障碍组Barthel评分均明显高于认知障碍组,差异有统计学意义(P<0.05)。结论急性脑梗死患者认知功能障碍的发生率较高,应密切关注相关危险因素,积极预防、治疗,采取危险因素预防、积极治疗基础疾病、康复锻炼、心理干预等预防措施。
Objective To explore the risk factors and preventive measures of cognitive impairment in patients with acute cerebral infarction.Methods 239 patients with acute cerebral infarction admitted to our hospital from May 2017 to May 2019 were assessed with the Simple Mental State Scale.According to whether the patients had cognitive impairment,they were divided into cognitive impairment group(n=55)and non-cognitive impairment group(n=184).The risk factors of cognitive impairment of patients with acute cerebral infarction was analyzed by univariate and multivariate methods.Results The incidence of cognitive impairment in patients with acute cerebral infarction was 23.01%(55/239).Multivariate Logistic regression analysis showed that age,history of diabetes,history of stroke,history of cerebrovascular disease,history of hypertension,NIHSS score>10 scores,multiple cerebral infarction,left hemispheric cerebral infarction and artery plaque are the risk factors for cognitive impairment after acute cerebral infarction(P<0.05).After active treatment and rehabilitation training for the two groups of patients,the Barthel score of the two groups of patients improved,the scores after 3 months of treatment was significantly higher than the scores of 1 month after treatment(P<0.05);At month and 3 months of treatment,the Barthel score of the non-cognitive impairment group was significantly higher than that of the cognitive impairment group,and the difference was statistically significant(P<0.05).Conclusion The incidence of cognitive impairment in patients with acute cerebral infarction is higher.We should pay close attention to the related risk factors,actively prevent and treat them,and take preventive measures such as risk factors prevention,active treatment of basic diseases,rehabilitation exercise and psychological intervention.
作者
刘娜
路学荣
孙雪美
Liu Na;Lu Xuerong;Sun Xuemei(Department of Neurology,Shenyang Seventh People's Hospital,Shenyang,Liaoning,110003,China)
出处
《当代医学》
2020年第30期80-83,共4页
Contemporary Medicine
关键词
急性脑梗死
认知功能障碍
预防措施
Acute cerebral infarction
Cognitive impairment
Preventive measures
