摘要
目的:分析探讨脑卒中亚急性期患者认知功能现况及影响因素。方法:选择2020年4月至2021年12月收治的120例脑卒中亚急性期住院患者,采用简易智力状态检查量表(Mini-mental State Examination,MMSE)和蒙特利尔认知评估量表(Montreal Cognitive Assessment Scale,Mo CA)对患者的认知功能进行评估。根据患者的认知功能,将患者分为认知功能正常组与认知功能障碍组。对2组患者的基线人口统计学及临床资料进行比较。采用单因素分析和多因素logistic回归分析探讨脑卒中亚急性期患者认知功能的影响因素。结果:120例脑卒中亚急性期患者中,合并认知功能障碍患者56例(46.67%)。单因素分析结果显示,2组患者的性别、体质指数(body mass index,BMI)、职业、家庭年收入、住院时间、吸烟史和糖尿病史的差异无统计学意义(P>0.05)。认知功能障碍组患者的年龄以及饮酒史、文化程度较低者、高血压史和高血脂史所占比例和美国国立卫生研究院神经功能缺损评分均显著高于认知功能正常组(P<0.05)。logistic多元回归分析结果显示,高龄、饮酒史、文化程度较低、高血压史、高血脂史和美国国立卫生研究院神经功能缺损高评分是脑卒中亚急性期患者合并认知功能障碍的独立影响因素(P<0.05)。结论:脑卒中亚急性期患者合并认知功能障碍的问题较为普遍,其中高龄、饮酒史、文化程度较低、高血压史、高血脂史和美国国立卫生研究院神经功能缺损高评分是合并认知功能障碍的主要影响因素,应根据这些影响因素制定相应的干预措施,改善脑卒中亚急性期患者的认知功能水平。
Objective:To analyze the status and influencing factors of cognitive function in patients with subacute stroke.Methods:120 hospitalized patients with subacute stroke from April 2020 to December 2021 were selected as the research objects.Mini-mental State Examination(MMSE)and Montreal Cognitive Assessment(MoCA)were used to evaluate the cognitive function of patients.According to the cognitive function survey results,patients were divided into normal cognitive function group and cognitive impairment group.The basic data and clinical data of the two groups were compared and analyzed,Univariate analysis and multivariate logistic regression analysis were carried out to explore the influencing factors of cognitive function in patients with subacute stroke.Results:Among the 120 patients with subacute stroke,56 patients were complicated with cognitive impairment,and the incidence of cognitive impairment was 46.67%.According to univariate analysis,there was no significant difference between the two groups in terms of gender,body mass index(BMI),occupation,annual family income,length of hospitalization,smoking history and diabetes(P>0.05),while the cognitive impairment group had older average age,more alcohol consumption,lower educationlevel,higherincidence of hypertension and hyperlipidemia and higher National Institute of Health Stroke Scale,(NIHSS)score than those in the normal cognitive function group(P﹤0.05).Logistic multivariate analysis showed that older age,alcohol consumption history,lower education level,history of hypertension or hyperlipidemia were independent risk factors of cognitive impairment in patients with subacute stroke(P<0.05).Conclusion:Cognitive impairment in patients with subacute stroke is common.Among them,older age,alcohol consumption history,lower education level,history of hypertension or hyperlipidemia are the main influencing factors of cognitive impairment.Corresponding intervention measures should be taken according to these influencing factors to improve the cognitive function in patien
作者
赵新鲜
阮春凤
ZHAO Xinxian;RUAN Chunfeng(Department of Nursing,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)
出处
《神经病学与神经康复学杂志》
2022年第2期54-61,共8页
Journal of Neurology and Neurorehabilitation
关键词
脑卒中
亚急性期
认知功能
影响因素
Stroke
Subacute phase
Cognitive function
Influence factor
