摘要
海带中提取的岩藻聚糖硫酸酯是一种含有岩藻糖和硫酸根离子的结构复杂的硫酸多糖,影响岩藻聚糖硫酸酯活性的因素有分子量、硫酸根含量、硫酸根的取代位置、单糖的组成等指标,不同物质不同提取方法和降解方法产生不同结构的多糖,其不同结构产生抗凝血、降血脂、抗病毒、抗肿瘤、提高免疫力、抗氧化、抗疲劳、促益生菌生长等特异药理学活性,硫酸多糖研究最早且最广泛的活性是其抗凝血活性。对海带岩藻聚糖硫酸酯的抗凝血活性进行了综述,并对其应用前景进行展望,为其深度开发利用提供参考。
Fucoidan extracted from Laminaria japonica is a sulfated polysaccharide with complex structure containing fucose and sulfate ion,the factors that affect the activity of fucoidan include the molecular weight,the content of sulfate radical,the substitution position of sulfate radical and the composition of monosaccharides,its different structures produce specific pharmacological activities such as anticoagulation,hypolipidemic,antivirus,anti-tumor,enhancing immunity,anti-oxidation,anti-fatigue,promoting probiotic growth,etc.In this paper,the anticoagulant activity of fucoidan from Laminaria japonica was reviewed,and the application prospect of fucoidan was forecasted,it provides a reference for its further development and utilization.
作者
郭峰君
易灵红
杨玉霞
杨乐乐
GUO Feng-jun;YI Ling-hong;YANG Yu-xia(Beihai Vocational College,Beihai,Guangxi 536000)
出处
《安徽农业科学》
CAS
2020年第19期1-3,8,共4页
Journal of Anhui Agricultural Sciences
基金
2016年度广西高校中青年教师基础能力提升项目(KY2016 YB756)。
关键词
海带
岩藻聚糖硫酸酯
抗血栓
活性
Laminaria japonica
Fucoidan
Antithrombotic
Activity
