摘要
[目的]了解1977—2016年海宁市女性乳腺癌40年发病动态、流行特征和变化规律,为制定乳腺癌防控策略与措施提供科学依据。[方法]应用海宁市肿瘤登记系统病例报告资料,计算女性乳腺癌粗发病率、中标率、累积率、截缩率、年度变化百分比(APC)等指标,并划分不同时间段对各年龄组发病率作比较。[结果]乳腺癌发病2392例,粗发病率为18.97/10万,中标率为11.80/10万,占女性恶性肿瘤病例的13.23%,居女性癌症的第2位,仅次于肺癌。从不同时间段年龄组发病率高峰看:1977—1986年70~岁组为高峰,发病率为30.00/10万;1987—1996年50~岁组为高峰,发病率为27.76/10万;1997—2006年45~岁组为高峰,发病率为40.04/10万;2007—2016年50~岁组为高峰,发病率达到80.37/10万。从年度变化分析看,发病率从1977年的5.00/10万,到2016年上升到56.88/10万。1977—1996年20年间发病率和中标率APC分别为2.3%(95%CI:0.7%~4.0%)和0.5%(95%CI:-1.3%~2.3%),1997—2016年后20年分别为10.1%(95%CI:8.2%~12.1%)和10.5%(95%CI:8.4%~12.6%)。[结论]女性乳腺癌呈快速上升态势,应进一步加强乳腺癌的预防控制工作。
[Purpose] To analyze the trends of female breast cancer incidence from 1977 to 2016 in Haining. [Methods] The data of female breast cancer were collected from Haining cancer registration. The crude incidence,ASR China rate,cumulative rate,truncation rate,percentage of annual change(APC%) of breast cancer in women were calculated. The incidence rates of each age group were compared in different time periods. [Results] There were total 2392 cases of female breast cancer reported during 1977 to 2016 in Haining with a crude incidence of 18.97/105. The incidence ASR China was 11.80/105,accounting for 13.23% of all cases of malignant tumors in women and ranking the second. The peak incidence was 30.00/105 in age group 70-year from 1977 to1986;that was 27.76/105 in the age group 50-years from 1987 to 1996;that was 40.04/105 in the age group 45-years from 1997 to 2006;that was 80.37/105 in age group 50-years from 2007 to2016. The incidence rose from 5.00/105 in 1977 to 56.88/105 in 2016. During 1977 to 1996,the APC for crude incidence and ASR China were 2.3%(95% CI:0.7% ~4.0%) and 0.5%(-1.3% ~2.3%),respectively;while during 1997 to 2016 the APC of crude rate and ASR China was 10.1%(8.2%~12.1%) and 10.5%(8.4%~12.6%),respectively. [Conclusion] There is a rapidly rising trend of female breast cancer incidence in Hangning in last 40 years,and prevention and control of female breast cancer should be strengthened.
作者
朱云峰
沈永洲
王乐
白卿长
杨靖
祝丽娟
ZHU Yun-feng;SHEN Yong-zhou;WANG Le;BAI Qing-chang;YANG Jing;ZHU Li-juan(Cancer Research Institute,Haining Hospital of Traditional Chinese Medicine,Haining 314400,China;Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital),Hangzhou 310022,China;Institute of Cancer and Basic Medicine(ICBM),Chinese Academy of Sciences Hangzhou 310022,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2020年第8期592-595,共4页
China Cancer
关键词
肿瘤登记
乳腺肿瘤
发病率
流行趋势
浙江
cancer registry
breast cancer
incidence rate
epidemiological trends
Zhejiang
