摘要
目的利用中医四诊仪观察慢性肾脏病(CKD)5期血液透析与非血液透析患者中医证型分布及相关规律。方法采用中医四诊仪测试的方法,收集100例上海中医药大学附属曙光医院CKD5期患者(其中血液透析患者60例,非透析患者40例)的中医四诊资料,整理其基本信息及生化报告资料进行分析,研究对比CKD5期患者中医证型及其与证型相关生化指标肌酐、血红蛋白、B型利钠肽(BNP)之间的相关性。结果中医四诊仪分析100例CKD5期透析与非透析患者的证型分布具有一定规律,肾阳虚和心气虚最常见(肾阳虚35%,心气虚33%),且透析组与非透析组各证型之间比较差异有统计学意义(P<0.05)。肾阳虚证中透析组血透前与非透析组肌酐水平、心气虚证型下两组间BNP水平、两组脾气虚证型下血红蛋白水平比较差异均具有统计学意义(P<0.05),而心血虚证型下两组之间血红蛋白水平比较差异无统计学意义(P>0.05)。结论CKD5期透析与非透析患者的证型分布具有一定规律,心气虚证BNP水平、脾气虚证血红蛋白水平具有相关性,心血虚证血红蛋白水平不具有相关性。
Objective To observe the distribution and correlation of TCM Syndrome types of hemodialysis and non-hemodialysis patients with chronic kidney disease stage 5(CKD5)by four diagnostic apparatus of TCM.Methods The four diagnostic instruments of TCM were used to collect the data of 100 patients with stage 5 hemodialysis(including 60 hemodialysis patients and 40 non-dialysis patients)in Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine.The basic information and biochemical report data were analyzed to study the correlation between CKD5 patients′TCM syndrome type and creatinine,hemoglobin,BNP.Results The distribution of syndrome types in 100 patients with CKD5 dialysis and non-dialysis was regular.Deficiency of kidney-yang and deficiency of heart-qi were the most common(35%of kidney-yang deficiency and 33%of heart-qi deficiency).There was significant difference between Dialysis Group and non-dialysis group(P<0.05).There were significant differences in creatinine levels before hemodialysis and non-dialysis,BNP levels in heart-qi Deficiency Syndrome and hemoglobin levels in spleen-qi Deficiency Syndrome between the two groups(P<0.05).There was no significant difference in hemoglobin level between the two groups with heart-blood deficiency syndrome(P>0.05).Conclusion There is a correlation in the distribution of syndrome types between CKD stage 5 dialysis and non-dialysis patients.The BNP level of the heart-qi deficiency syndrome and the hemoglobin level of the spleen-qi deficiency syndrome are correlated,and the hemoglobin level of the heart-blood deficiency syndrome is not correlated.
作者
郑淇丹
金坤
何立群
陈刚
ZHENG Qi-dan;JIN Kun;HE Li-qun;CHEN Gang(Department of Nephrology,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Key Laboratory of Liver and Kidney Diseases,Ministry of Education,Shanghai 201203)
出处
《世界中西医结合杂志》
2020年第8期1507-1510,共4页
World Journal of Integrated Traditional and Western Medicine
基金
何立群上海市名老中医学术经验研究工作室(SHGZS-2017027)
上海市浦东新区卫生系统重点学科群建设资助(PWZxq2017-07)
上海市进一步加快中医药事业发展三年行动计划建设项目[ZY(2018-2020)-CCCX-2003-08,ZY(2018-2020)-FWTX-7005]。
关键词
慢性肾脏病5期
血液透析
非血液透析
中医四诊仪
中医证型
生化指标
Chronic Kidney Disease Stage 5
Hemodialysis
Non-Hemodialysis
TCM Four-Diagnosis Instrument
TCM Syndrome Types
Biochemical Indicators
