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枣庄市乙型病毒性肝炎血清流行病学调查研究 被引量:5

Seroepidemiological investigation of hepatitis B in Zaozhuang City
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摘要 目的了解枣庄市乙型病毒性肝炎流行现状。方法整群随机抽样法选取2019年1月至10月枣庄市常住居民250例为调查对象。采用入户调查的方式进行问卷调查和外周血标本采集,收集性别、年龄、职业类型及民族,化学发光定量法检测乙肝表面抗原(HBSAg)、核心抗体(抗HBc)、乙肝表面抗体(抗HBs)水平。结果 250例调查对象中HBsAg阳性率为4.80%,抗HBc阳性率为40.80%,抗HBs阳性率为41.60%。男性抗HBc阳性率明显高于女性,差异有统计学意义(P<0.01)。HBsAg、抗HBc、抗HBs阳性率在不同职业类型居民中比较差异均有统计学意义(均P<0.05)。结论枣庄市乙型病毒性肝炎免疫防控效果较好,≤18岁学龄期儿童青少年HBsAg阳性率已清零,但成年人的感染率仍需进一步降低,应针对不同性别和职业类型居民采取针对性防控措施。 Objective To understand the prevalence of hepatitis B in Zaozhuang City.Methods A total of 250 permanent residents in Zaozhuang City from January to October 2019 were selected as the subjects by cluster random sampling.The methods of household survey were questionnaire survey and peripheral blood sample collection.Gender,age,occupation type and nationality were collected.The levels of HBsAg,anti HBC and anti HBS were detected by chemiluminescence quantitative method.Results The positive rates of HBsAg,anti HBC and anti HBS were 4.80%,40.80%and 41.60%respectively.The positive rates of anti HBC in men were significantly higher than that in women(P<0.01).The positive rates of HBsAg,anti HBC and anti HBS in different occupation types of residents were statistically significant(P<0.05);the positive rates of HBsAg,anti HBC and anti HBS in residents of different nationalities were not statistically significant(P>0.05).Conclusion The immune prevention and control effect of hepatitis B in Zaozhuang City is better.The positive rate of HBsAg in school-age children and adolescents under 18 years old has been cleared,but the infection rate in adults still needs to be further reduced.Targeted prevention and control measures should be taken for residents of different genders and occupational types.
作者 吴冰 WU Bing(Department of Epidemiology,Zaozhuang Center for Disease Control and Prevention,Zaozhuang Shandong 277101,China)
出处 《中国卫生工程学》 CAS 2020年第4期506-508,共3页 Chinese Journal of Public Health Engineering
基金 枣庄市科技卫生发展计划项目(2018033)。
关键词 乙型病毒性肝炎 流行病学调查 枣庄市 Hepatitis B Epidemiological survey Zaozhuang City
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