摘要
目的探讨多层螺旋CT(MSCT)技术四期增强扫描下肝细胞肝癌双动脉期的强化特点,并分析不同肿瘤病理分化之间的相关性。方法选取广西科技大学第一附属医院2013年1月至2015年3月收治的120例多层螺旋CT技术四期增强扫描并经手术病理证实的肝细胞肝癌患者的120例肿瘤病灶。根据双动脉期肿瘤内血管强化、肝实质密度以及内肿瘤实质特点,将肝细胞肝癌患者的120例肿瘤病灶分为3组。分别为肿瘤实质强化的参照组,肿瘤无明显强化的对照组,肿瘤实质强化与肿瘤血管强化同时存在的观察组。结果在31例高分化病灶中,对照组中检出率74.19%明显高于观察组22.58%、参照组3.23%,差异有统计学意义(P<0.001),在43例中分化病灶中,观察组60.47%、参照组32.56%,明显高于对照组6.52%,差异有统计学意义(P<0.005)。在37例低分化病灶中,观察组64.86%、参照组29.73%,明显高于对照组5.41%,差异有统计学意义(P<0.001)。结论螺旋CT四期动态增强扫描双动脉期强化特点与肝细胞癌分化程度之间关系密切,在肿瘤分化程度不断降低时,动脉期早期肿瘤血管逐渐增多,且肿瘤面积逐渐增大,说明MSCT技术四期增强扫描可为临床提供更多的预后信息以及诊治依据具有重要意义。
Objective To investigate the enhancement characteristics of hepatocellular carcinoma(HCC)in doublearterial phase under multi-phase spiral CT(MSCCT)technique with four-phase enhancement scan,and analyze the correlation between pathological differentiation of different tumors.Methods A total of 120 patients with hepatocellular carcinoma who underwent four-phase contrast-enhanced scanning with multislice spiral CT and were confirmed by surgery and pathology were selected from the First Affiliated Hospital of Guangxi University of Science and Technology from January 2013 to March 2015.According to the characteristics of intratumoral vascular enhancement,hepatic parenchymal density and intratumoral parenchyma in the double arterial phase,120 patients with hepatocellular carcinoma were divided into three groups.They were the reference group with enhanced tumor parenchyma,the control group without obvious enhancement of tumor,and the observation group with both enhanced tumor parenchyma and enhanced tumor vessels.Results Among the 31 highly differentiated lesions,74.19%were detected in the control group,which was significantly higher than the observation group(22.58%)and the reference group(3.23%).The difference was significant(P<0.001).Among the 53 well-differentiated lesions,49.06%of the observation group and 45.28%of the reference group were significantly higher than the control group of 5.66%,the difference was significant(P<0.001).Among the 37 poorly differentiated lesions,64.86%in the observation group and 29.73%in the reference group were significantly higher than the control group(5.41%),and the difference was significant(P<0.001).Conclusion There is a close relationship between the enhancement characteristics of double-arterial phase of spiral CT four-phase dynamic contrast-enhanced scan and the differentiation degree of hepatocellular carcinoma.When the degree of tumor differentiation is decreasing,the tumor blood vessels in the early arterial phase gradually increase,and the tumor area gradually increases.Thi
作者
陈天忠
苏江
罗秉庆
CHEN Tianzhong;SU Jiang;LUO Bingqing(First Affiliated Hospital of Guangxi University of Science and Technology,Liuzhou,Guangxi 545002,China)
出处
《大医生》
2020年第3期24-28,共5页
Doctor
基金
广西壮族自治区卫生厅自筹经费科研课题(编号:Z2013666)。
关键词
多层螺旋CT
肿瘤实质强化
双动脉期
肝细胞肝癌
multi-slice spiral CT
tumor parenchymal enhancement
dual arterial phase
hepatocellular carcinoma
