摘要
目的分析杜仲黑茶的营养成分,探索其对辅助降血压、降血糖和降血脂的功效。方法参考GB5009.124-2016标准方法和GB 19965-2005附录A相关规定,检测杜仲黑茶中氨基酸和矿物元素。采用两肾一夹法建立肾性高血压大鼠模型;高脂饲料联合地塞米松磷酸钠注射液建立高血糖大鼠模型;高脂膳食诱导高脂血症大鼠模型,观察杜仲黑茶对大鼠血压、血糖及血脂水平的影响。结果杜仲黑茶含甲硫氨酸、缬氨酸及赖氨酸等16种氨基酸,锌、铜及铁等19种矿物元素。杜仲黑茶明显降低大鼠的血压(P<0.05);杜仲黑茶显著降低大鼠血糖值及血糖曲线下面积AUC(P<0.05);杜仲黑茶显著降低大鼠的总胆固醇和甘油三酯水平(P<0.05)。结论杜仲黑茶具有辅助降低高血压、高血糖及高血脂的功效。
Objective To analyze the nutritional constituents of Eucommia ulmoides black tea and explore the efficacy of assisting in lowering blood pressure,blood sugar and blood lipids.Methods Amino acids and mineral elements in Eucommia ulmoides black tea were tested according to the GB5009.124-2016 standard method and the relevant regulations in Appendix A of GB 19965-2005.The twokidneys one-clamp method was used to establish rat renal hypertension;high-fat diets combined with dexamethasone sodium phosphate injection were used to establish hyperglycemic rats;high-fat diet was used to establish hyperlipidemia rats.Then,the blood pressure,blood glucose and blood lipid levels in rats were-examined after treatment with Eucommia ulmoides black tea.Results Eucommia ulmoides black tea contains 16 amino acids such as methionine,valine and lysine,and 19 mineral elements such as zinc,copper and iron.After the treatment with Eucommia ulmoides black tea,the blood pressure of hypertensive rats was significantly reduced(P<0.05);the blood glucose level and the area under the blood glucose curve of hyperglycemic rats were significantly reduced(P<0.05);and the level of total cholesterol and triglyceride were significantly reduced(P<0.05).Conclusion Eucommia ulmoides black tea has been shown to help reducing hypertension,hyperglycemia and hyperlipidemia.
作者
穆文碧
张建永
李明丹
曾宏亮
段灿灿
谢友旺
Mu Wenbi;Zhang Jianyong;Li Mingdan;Zeng Hongliang;Duan Cancan;Xie Youwang(School of Pharmacy,Zuni Medical University,Zunyi Guizhou 563099,China;Hunan Drug Safety Evaluation and Research Center,Changsha Hunan 410208,China;Hunan Academy of Traditional Chinese Medicine,Changsha Hunan 410013,China;Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education,Zunyi Medical University,Zunyi Guizhou 563099,China;Zhangjiajie Tea Kunyuan Eucommia Biotechnology Development Co.,Ltd.,Zhangjiajie Hunan 427200,China)
出处
《遵义医科大学学报》
2020年第3期276-281,共6页
Journal of Zunyi Medical University
基金
贵州省中药民族药2011协同创新中心项目(NO:黔教科研发[2012]311)
贵州省教育厅科技拔尖人才支持项目(NO:黔教合KY字[2017]078)
贵州省社会攻关项目子项目(NO:黔科合支撑[2016]2854)。
关键词
杜仲黑茶
高血压
高血糖
高脂血症
Eucommia ulmoides black tea
hypertension
hyperglycemia
hyperlipidemia