摘要
目的 总结近年来有关杜仲化学成分及药理作用研究进展,为其进一步开发利用提供依据。方法 以“杜仲”“化学成分”“药理作用”“Eucommia ulmoides”“Chemical composition”“Pharmacologicalactivity”等作为关键词在知网、万方、维普、PubMed、Geenmediacal等数据库查询相关文献。在已有文献基础上对杜仲的化学成分、药理作用、临床应用研究进展进行综述。结果 通过在中国知网和PubMed数据库中检索相关文献,对杜仲相关的最新研究成果进行总结归纳,本文综述了杜仲的化学成分包括木脂素类、环烯醚萜类、黄酮类、苯丙素类以及萜类等其他类成分;杜仲具有调节血糖、血脂、血压,抗骨质疏松、抗炎、抗氧化、保护肝肾、免疫调节、抗肿瘤、抗癌等作用。结论 杜仲中含有木脂素类、环烯醚萜类、黄酮类、苯丙素类等化学成分;具有降血糖、降血脂、抗氧化、免疫调节等药理作用;目前主要用于治疗糖尿病、高脂血症、骨质疏松等疾病。
Objective To summarize the research progress on the chemical components and pharmacological effects of Eucommia ulmoides in recent years,and provide a basis for its further development and utilization.Methods Using keywords such as“Eucommia ulmoides”“chemical components”“pharmacological effects”“European ulmoides”“chemical composition”and“pharmacological activity”relevant literature was searched in databases such as CNKI,Wanfang,VIP,PubMed,and Geenmedial.Summarize the research progress on the chemical composition,pharmacological effects,and clinical applications of Eucommia ulmoides based on existing literature.Results By searching relevant literature on CNKI and PubMed databases,the latest research achievements related to Eucommia ulmoides were summarized and summarized.This article reviews the chemical components of Eucommia ulmoides,including lignans,cycloene terpenes,flavonoids,phenylpropanoids,and other types of terpenes;Eucommia ulmoides has functions such as regulating blood sugar,blood lipids,blood pressure,anti osteoporosis,anti-inflammatory,antioxidant,liver and kidney protection,immune regulation,anti-tumor,and anti-cancer.Conclusion Eucommia ulmoides contains chemical components such as lignans,iridoids,flavonoids,and phenylpropanoids;It has pharmacological effects such as lowering blood sugar,lowering blood lipids,antioxidation,and immune regulation;At present,it is mainly used to treat diabetes,hyperlipidemia,osteoporosis and other diseases.
作者
张睿哲
李倩
裴娟
党绒
杨玉婷
王川
ZHANG Ruizhe;LI Qian;PEI Juan;DANG Rong;YANG Yuting;WANG Chuan(Shaanxi University of Chinese Medicine,Shaanxi Xianyang712046,China)
出处
《陕西中医药大学学报》
2024年第4期87-91,共5页
Journal of Shaanxi University of Chinese Medicine
基金
陕西省科技厅一般项目-青年项目(2023-JC-QN-0821)
陕西省教育厅一般专项项目(22JK0348)
大学生创新创业训练计划项目(S202210716003)
陕西中医药大学附属医院院级项目(2020MS019)。
关键词
杜仲
化学成分
药理作用
临床应用
Eucommia ulmoides
Chemical composition
Pharmacological effects
Clinical application
