摘要
目的探讨四君子汤加减治疗慢性胃炎的临床疗效及其安全性。方法选取伊宁县中医院2017年2月—2019年2月收治的慢性胃炎患者100例,采用随机综合序贯法分为参照组与试验组,每组50例。参照组给予常规治疗,试验组在对照组基础上给予四君子汤治疗。比较两组临床疗效,治疗前后血清胃动素(MTL)、生长抑素(SS),并观察两组不良反应发生情况。结果试验组总有效率高于参照组(P<0.05)。治疗前两组MTL、SS比较,差异无统计学意义(P>0.05);治疗后试验组MTL低于参照组,SS高于参照组(P<0.05)。试验组不良反应发生率低于参照组(P<0.05)。结论四君子汤加减治疗慢性胃炎的临床疗效确切,可有效调节胃肠道动力,且安全性较高。
Objective To investigate the clinical efficacy and safety of Sijunzi decoction in the treatment of chronic gastritis.Methods A total of 100 cases of patients with chronic gastritis were selected from February 2017 to February 2019 in Yining Hospital of Traditional Chinese Medicine,which were divided into reference group and experimental group according to random comprehensive sequential,50 cases in each group.The control group was given routine treatment,and the experimental group was given Sijunzi decoction based on the control group.The clinical effect,serum motilin(MTL)and somatostatin(SS)before and after treatment were compared between the two groups.The adverse reactions of the two groups were observed.Results The total effective rate of the experimental group was higher than the reference group(P<0.05).There was no significant difference in MTL and SS between the two groups before treatment(P>0.05);after treatment,the MTL of the experimental group was lower than the reference group,and SS was higher than the reference group(P<0.05).The incidence rate of adverse reactions in the experimental group was lower than the reference group(P<0.05).Conclusion The clinical effect of Sijunzi decoction in the treatment of chronic gastritis is accurate,it can effectively regulate the gastrointestinal motility,and with high safety.
作者
郑志祥
ZHENG Zhi-xiang(Department of Pharmacy,Yining Hospital of Traditional Chinese Medicine,Yining 835100,China)
出处
《临床合理用药杂志》
2020年第15期27-28,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
胃炎
四君子汤
治疗结果
安全性
Gastritis
Sijunzi decoction
Treatment outcome
Safety
