摘要
目的比较雷尼替丁和奥美拉唑治疗浅表性胃炎的临床效果。方法选取2018年6月~2019年6月在我院接受治疗的88例浅表性胃炎患者作为研究对象,采用随机数字表法分为对照组和观察组,各44例。对照组采用雷尼替丁治疗,观察组采用奥美拉唑治疗,比较两组治疗总有效率、临床症状(胃痛、反酸、饱胀、恶心)消失时间、平均疗程及不良反应发生情况。结果观察组总有效率为95.45%,高于对照组的93.18%,但差异无统计学意义(P>0.05);观察组胃痛、反酸、饱胀、恶心消失时间及疗程均短于对照组,差异有统计学意义(P<0.05);治疗期间,观察组不良反应发生率为6.81%,低于对照组的9.09%,但差异无统计学意义(P>0.05)。结论雷尼替丁和奥美拉唑治疗浅表性胃炎均可获得良好的效果,且无严重不良反应。但奥美拉唑可在短时间内减轻患者症状,起效较快,疗程短,可作为治疗浅表性胃炎的首选药物。
Objective To compare the clinical effects of ranitidine and omeprazole in the treatment of superficial gastritis.Methods A total of 88 patients with superficial gastritis treated in our hospital from June 2018 to June 2019 were selected as the research object.They were divided into a control group and an observation group with a random number table method,with 44 cases in each group.The control group was treated with ranitidine and the observation group was treated with omeprazole.The total treatment efficiency,clinical symptoms(stomach pain,acid reflux,fullness,nausea)disappearance time,average course of treatment and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 95.45%,higher than that of the control group of 93.18%,but the difference was not statistically significant(P>0.05);the time of disappearance of gastric pain,acid reflux,fullness,and nausea in the observation group and the duration of treatment were shorter than the control group,the difference was statistically significant(P<0.05);during treatment,the incidence of adverse reactions in the observation group was 6.81%,which was lower than 9.09%in the control group,but the difference was not statistically significant(P>0.05).Conclusion Ranitidine and omeprazole can achieve good results in the treatment of superficial gastritis without serious adverse reactions.However,omeprazole can alleviate the symptoms of patients in a short period of time;it has a faster onset and a shorter course of treatment,and can be used as the first choice for the treatment of superficial gastritis.
作者
任琳
REN Lin(Department of Internal Medicine,Zhuanghe Second People's Hospital,Zhuanghe 116413,Liaoning,China)
出处
《医学信息》
2020年第12期141-142,共2页
Journal of Medical Information
