摘要
目的:分析丁苯酞注射液治疗老年急性脑梗死(ACI)患者的疗效及其对脑血流动力学和脑血管储备能力的影响。方法:选取2018年1月至2019年5月在新密市第一人民医院接受诊治的ACI患者48例作为研究对象进行对比研究。根据不同用药方式将所选48例分为常规组20例(奥扎格雷钠十阿司匹林)与观察组28例(常规组用药基础上加丁苯酞注射液)。通过14d治疗后观察两组患者的治疗效果、血流动力学以及脑血管储备能力。结果:观察组患者的治疗效果优于常规组,组间比较差异有统计学意义(P<0.05);治疗后观察组患者的全血粘度、血浆黏度、纤维蛋白原以及红细胞压积指标显著优于常规组。治疗后观察组患者的脑血管储备功能以及脉动指数显著优于常规组。结论:丁苯酞注射液治疗老年ACI患者的疗效及其对脑血流动力和脑血管储备能力的影响显著。
Objective:To analyze the curative effect of Butyl phthalide injection for the elderly pa-tients with acute cerebral infarction(ACI)and its effect on cerebral blood flow dynamics and cerebro-vascular reserve capacity.Methods:From January 2018 to May 2019,48 patients with ACI were re-cruited as the subjects.According to different medication methods,The selected 48 cases were divided into the routine group(20 cases with ozagrel sodium+aspirin)and the experimental group(28 cases combined with butylphthalide injection in addition to routine treatment).14 days after treatment,the therapeutic effect,hemodynamics and cerebral vascular reserve ability of the two groups were ob-served.Results:The curative effect of the experimental group was satisfied and superior to that of the routine group;and the difference was statistically significant(P<<0.05).The whole blood viscosity,the plasma viscosity,the fibrinogen and the hematocrit index in the experimental group were signifi-cantly superior to those in the routine group.The function of the cerebrovascular reserve and the pul-sation index in the experimental group were significantly superior to those of the conventional group.Conclusion:The effect of butylphthalide injection for elderly patients with ACI and its effect on cere-bral hemodynamics and cerebrovascular reserve capacity is significant,worth popularizing.
作者
刘湘媛
裴巧玲
LIU Xiangyuan;PEI Qiaoling(Department of Neurology,Xinmi First People's Hospital,Xinmi(452370),Henan,China)
出处
《癫痫与神经电生理学杂志》
2020年第3期145-148,共4页
Journal of Epileptology and Electroneurophysiology(China)
关键词
丁苯酞注射液
急性脑梗死(ACI)
临床疗效
脑血流动力学
脑血管储备能力
Butylphthalide injection
acute cerebral infarction(ACI)
curative effect
cerebral hemodynamics
cerebrovascular reserve capacity
