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65岁以上老年人颈动脉斑块与血流变的关系研究 被引量:5

Association between carotid plaque and hemorheology in the elderly above 65 years of age
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摘要 目的研究社区门诊65岁以上老年人颈动脉斑块形成与血流变异常的关系。方法选择社门诊区登记的65岁以上老年人共120例,其中健康者45例(对照组),心脑血管疾病患者75例(观察组);采用多普勒超声检测颈动脉斑块,自动血流变测试仪检测血流变指标,包括全血粘度、血浆粘度、红细胞压积(HCT)、血沉(ESR)、血浆纤维蛋白原(Fib)。结果观察组颈动脉斑块形成率和数量明显高于对照组,差异有统计学意义(P<0.05)。观察组全血粘度、血浆粘度、HCT、Fib水平均明显高于对照组,ESR降低,差异有统计学意义(P<0.05)。结论65岁以上老年人心脑血管疾病的发生与颈动脉斑块形成与血流变异常有关。 Objective To investigate the association between carotid plaque formation and abnormal hemorheology in the elderly above 65 years of age in the community outpatient service.Methods A total of 120 elderly residents who were registered in the community outpatient service were enrolled,among whom there were 45 healthy residents(control group)and 75 patients with cerebrovascular and cardiovascular diseases(observation group).Color Doppler ultrasound was used to detect carotid plaque,and an automatic hemorheologicalanalyzer was used to measure hemorheologicalindices,including whole blood viscosity,plasma viscosity,hematocrit(HCT),erythrocyte sedimentation rate(ESR),and plasma fibrinogen(Fib).Results The observation group had significantly higher rate of carotid plaque formation and number of carotid plaques than the control group(P<0.05).Compared with the control group,the observation group had significantly higher whole blood viscosity,plasma viscosity,HCT,and Fib level and a significantly lower ESR(P<0.05).Conclusion The development of cerebrovascular and cardiovascular diseases and carotid plaque formation are associated with abnormal hemorheologyin the elderly above 65 years of age.
作者 甘灵玲 GAN Ling-ling(Wuzhou Hospital of Integrated Traditional Chinese and Western Medicine,Wuzhou 543000,China)
出处 《心血管病防治知识(学术版)》 2019年第17期41-43,共3页 Prevention and Treatment of Cardiovascular Disease
关键词 颈动脉斑块 血流变 心脑血管疾病 Carotid plaque Hemorheology Cerebrovascular and cardiovascular diseases
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