摘要
目的探讨鼻内镜下二线减张法鼻中隔矫正术联合常规药物治疗变应性鼻炎伴鼻中隔偏曲的中期随访结果。方法回顾性分析2015年6月至2018年6月于贺州市人民医院治疗的102例变应性鼻炎伴鼻中隔偏曲患者的临床资料,按照治疗方法不同分为对照组和试验组,各51例。其中,对照组接受常规药物治疗,试验组接受鼻内镜下二线减张法鼻中隔矫正术联合常规药物治疗。比较两组患者治疗后1年的临床疗效,治疗前、治疗后6个月、治疗后1年的鼻阻力水平、健康调查简表(SF-36)评分以及复发情况。结果试验组的总有效率高于对照组[92. 00%(46/50)比69. 39%(34/49)](P <0. 05)。治疗后6个月、治疗后1年两组患者的鼻阻力水平均下降,且试验组低于对照组;两组患者的SF-36评分均升高,且试验组高于对照组。两组鼻阻力水平、SF-36评分的组间、时点间及组间和时点间交互作用比较差异有统计学意义(P <0. 05)。治疗后1年,试验组变应性鼻炎的复发率低于对照组[6. 00%(3/50)比22. 45%(11/49)](P <0. 01)。结论鼻内镜下二线减张法鼻中隔矫正术联合常规药物治疗变应性鼻炎伴鼻中隔偏曲的临床疗效显著,可降低鼻阻力与疾病术后复发风险,改善患者生活质量。
Objective To investigate the mid-term follow-up results of nasal septum correction by endoscopic two-line detension combined with conventional drugs for patients with allergic rhinitis with nasal septum deviation.Methods The clinical data of 102 patients with allergic rhinitis and nasal septum deviation treated in Hezhou People′s Hospital from Jun.2015 to Jun.2018 were retrospectively analyzed.According to different treatment methods,they were divided into a control group and a test group,each with 51 cases.The control group received conventional drug treatment,and the test group received nasal septum correction by endoscopic two-line detension combined with conventional drug treatment.The clinical efficacy at 1 year after treatment,levels of nasal resistance,scores from the MOS 36 item short form health survey(SF-36)before treatment,6 months after treatment,and 1 year after treatment,and recurrence of the two groups were compared.Results The total effective rate of the test group was higher than that of the control group[92.00%(46/50)vs 69.39%(34/49)](P<0.05).6 months after treatment and 1 year after treatment,the nasal resistance level of the two groups decreased,and the test group was lower than the control group;the SF-36 scores of both groups increased,and the test group was higher than the control group.There were statistically significant differences between groups,time points and interactions of group and time point in the level of nasal resistanceand SF-36 score(P<0.01).One year after treatment,the recurrence rate of allergic rhinitis in the test group was lower than that in the control group[6.00%(3/50)vs 22.45%(11/49)](P<0.05).Conclusion The clinical efficacy of nasal septum correction with endoscopic two-line nasal detension combined with conventional drugs in the treatment of allergic rhinitis with nasal septum deviation is significant,which can reduce the risk of nasal resistance and disease recurrence after surgery,and improve the quality of life of the patients.
作者
高波
邹贵龙
黄毅刚
蒋团斌
GAO Bo;ZOU Guilong;HUANG Yigang;JIANG Tuanbin(Department of Otolaryngology,Hezhou People′s Hospital,Hezhou 542899,China)
出处
《医学综述》
2020年第12期2489-2492,2497,共5页
Medical Recapitulate
关键词
变应性鼻炎
鼻中隔偏曲
鼻内镜下二线减张法鼻中隔矫正术
氯雷他定
丙酸氟替卡松鼻喷雾剂
鼻阻力
复发率
Allergic rhinitis
Nasal septum deviation
Nasal septum correction by endoscopic two-line detension
Loratadine
Fluticasone propionate nasal spray
Nasal resistance
Recurrence rate
