摘要
目的:探讨糖化白蛋白(GA)与HbA1c在糖尿病伴随葡萄糖-6-磷酸脱产氢酶(G6PD)缺乏人群的应用价值。方法:收集2012年8月-2016年4月期间中山大学附属中山医院286份标本,分别为健康组122例、糖尿病(DM)82例、G6PD缺乏症61例及糖尿病伴G6PD缺乏症组21例。检测四组人群GA与HbA1c水平,比较健康组与缺乏组,糖尿病组与糖尿病伴G6PD缺乏症组GA与HbA1c水平。结果:G6PD缺乏组及糖尿病伴G6PD缺乏组的HbA1c均偏低,且与健康组及糖尿病组的差异具有统计学意义(P<0.05)。G6PD缺乏组及糖尿病伴G6PD缺乏组与健康组及糖尿病组的GA无显著性差异(P>0.05)。结论:G6PD缺乏HbA1c结果假性偏低。GA则更能反映G6PD缺乏人群的血糖控制水平,临床医生针对G6PD缺乏人群,应选择合适指标进行血糖控制水平评估。
Objective:To explore the application value of GA and HbA1c in diabetes mellitus patients with G6PD deficiency.Methods:286 cases of blood and serum samples were collected at Zhongshan Hospital of Sun Yat-Sun University from August 2012 to April 2016.The blood samples were divided into normal control group(122 cases),diabetes group(82 cases),G6PD deficiency group(61 cases)and diabetes with G6PD deficiency group(21 cases).The value of GA,HbA1c was calculated in different groups and statistical analysis were excluded for evaluation of the differences.Results:The HbA1c results of G6PD deficiency group were lower than normal control group(P<0.05).The GA results were no significant difference between G6PD deficiency group and control group.Conclusion:G6PD deficiency caused low HbA1c results.The result of GA can better reflect the level of blood glucose control.When doctors evaluate blood glucose control for people with G6PD deficiency,they should select the appropriate indicators.
作者
胡耀宗
温冬梅
王伟佳
胡婷
王霞
田原
卢兰芬
HU Yaozong;WEN Dongmei;WANG Weijia(Clinical Laboratory Center,Zhongshan Hospital of Sun Yat-Sun University,Zhongshan City,Guangdong Province 528403)
出处
《医学理论与实践》
2020年第12期1911-1913,共3页
The Journal of Medical Theory and Practice
