摘要
目的分析深圳市STD门诊患者淋病奈瑟菌(NG)感染状况及相关因素,为制定干预措施提供依据。方法采用横断面调查研究方法,在2018年4月15日至5月16日收集深圳市6个区22家医疗机构的18~49岁、有过性行为、最近2周未使用过抗生素的STD门诊患者的相关信息和尿液标本,利用核酸扩增试验进行尿液NG感染检测。应用logistic回归分析NG感染的相关因素。结果8324例STD门诊患者中,NG感染率为2.4%(196/8324)。男性NG感染率(5.8%,148/2567)高于女性(0.8%,47/5742,χ^2=189.43,P<0.05)。年龄≤24岁(OR=2.11,95%CI:1.44~3.09),单身/离异/丧偶(OR=1.98,95%CI:1.38~2.84),最近3个月有临时性伴(OR=1.77,95%CI:1.29~2.43)是NG感染的相关因素。结论深圳市STD门诊患者的NG感染率较高,男、女性的NG感染率差异较大。应针对存在非婚性行为或有临时性伴的高危行为的STD门诊患者开展淋病筛查与干预及规范化治疗,减少淋病及其他STD的传播和流行。
Objective To understand the prevalence of Neisseria gonorrhoeae(NG)infection and related factors in outpatients of sexually transmitted disease(STD)in Shenzhen and provide scientific evidence for targeted intervention.Methods A cross-sectional study was conducted in STD outpatients who were aged 18-49 years,had had sexual intercourse,had not received antibiotics in the last 2 weeks and sought medical cares in 22 medical institutions in 6 districts of Shenzhen from 15 April,2018 to 16 May,2018,their basic information and urine samples were collected,and NG in urine sample was detected by nucleic acid amplification test.Logistic regression analysis was conducted to identify the related factors for NG infection.Results The information collection and sample collection were completed for 8324 STD outpatients,among these STD outpatients,196 were NG positive,with a positive rate of 2.4%(196/8324).The positive rate of NG in men(5.8%,148/2567)was higher than that in women(0.8%,47/5742)(χ^2=189.43,P<0.05).Aged 24 years or below(OR=2.11,95%CI:1.44-3.09),single/divorced/widowed(OR=1.98,95%CI:1.38-2.84),having casual sex in the last 3 months(OR=1.77,95%CI:1.29-2.43)were the related factors for NG infection.Conclusions We found that NG infection rate was high in STD outpatients in Shenzhen.The infection rates in men and in women differed obviously.It is necessary to conduct gonorrhea screening and intervention in STD outpatients with high-risk behaviors,such as extramarital and casual sex behaviors,and standardize the treatment to reduce the incidence and spread of gonorrhea and other STDs.
作者
王洪琳
蔡于茂
张春来
叶健滨
翁榕星
洪福昌
陈祥生
Wang Honglin;Cai Yumao;Zhang Chunlai;Ye Jianbin;Weng Rongxing;Hong Fuchang;Chen Xiangsheng(Shenzhen Center for Chronic Disease Prevention and Control,Shenzhen 518020,China;Institute of Dermatology and Hospital for Skin Diseases,Chinese Academy of Medical Sciences and Peking Union Medical Collage,Nanjing 210042,China;National Center for STD Control,Chinese Center for Disease Control and Prevention,Nanjing 210042,China)
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2020年第5期743-746,共4页
Chinese Journal of Epidemiology
基金
深圳市"医疗卫生三名工程"项目(SZSM 201611077)。
关键词
性传播疾病
淋病奈瑟菌
门诊患者
感染
相关因素
Sexually transmitted disease
Neisseria gonorrhoeae
Outpatient
Infection
Related factor
