摘要
目的对比分析血管性痴呆(VD)与阿尔茨海默病(AD)磁共振成像(MRI)影像结果。方法回顾性分析2017年4月~2019年4月本院收治的59例VD、42例AD患者临床资料,两组均接受MRI检查,比较两组MRI海马高度、颞角宽度、外侧裂宽度,脑白质疏松(LA)严重度,额叶、颞叶、顶叶、枕叶体积以及各脑叶脑血流参数。结果VD组MRI以脑内梗死灶为主要特征,AD组以海马萎缩为主要特征;VD组海马高度显著高于AD组(P<0.05),颞角宽度、外侧裂宽度均显著低于AD组(P<0.05),LA严重程度大于AD组(P<0.05),额叶、颞叶体积占比显著低于AD组(P<0.05),额叶、颞叶脑血流参数均显著低于AD组(P<0.05)。结论VD与AD患者MRI图像存在较大差异,MRI对VD与AD有较高的鉴别诊断价值。
Objective To compare and analyze the imaging results of magnetic resonance imaging(MRI)on vascular dementia(VD)and Alzheimer’s disease(AD).Methods The clinical data of 59 patients with VD and 42 patients with AD admitted to the hospital from April 2017 to April 2019 were retrospectively analyzed.MRI was performed in both groups.The hippocampal height,temporal angle width,lateral fissure width,leukoaraiosis(LA)severity,volumes of frontal lobe,temporal lobe,parietal lobe and occipital lobe,and cerebral blood flow parameters lobes were compared between the two groups under MRI.Results In MRI,VD group was mainly characterized by intracerebral infarction,and AD group was mainly characterized by hippocampal atrophy.The hippocampal height in VD group was significantly higher than that in AD group(P<0.05),and the width of temporal angle and width of lateral fissure were significantly lower than those in AD group(P<0.05),and the severity of LA was greater than that in AD group(P<0.05),and the volume ratio of frontal lobe and temporal lobe in VD group were significantly lower than those in AD group(P<0.05),the cerebral blood flow parameters of frontal lobe and temporal lobe were significantly lower than those in AD group(P<0.05).Conclusion MRI images of VD and AD patients were significantly different,and MRI had higher value in differential diagnosis of VD and AD.
作者
王天舒
杜冉
滕军放
WANG Tian-shu;DU Ran;TENG Jun-fang(Department of Neurology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)
出处
《中国CT和MRI杂志》
2020年第5期59-61,78,共4页
Chinese Journal of CT and MRI
关键词
血管性痴呆
阿尔茨海默病
磁共振成像
鉴别诊断
Vascular Dementia
Alzheimer’s Disease
Magnetic Resonance Imaging
Differential Diagnosis
