摘要
目的观察调中饮对儿童厌食症脾虚肝旺证临床疗效及胃电图、血清锌和血管活性肠肽(VIP)的影响。方法将80例厌食症脾虚肝旺证患儿采用随机数字表法分为治疗组和对照组,各40例。对照组予葡萄糖酸锌颗粒口服,治疗组予调中饮口服,2组均4周为1个疗程,2个疗程后统计疗效。结果治疗前,2组食欲、食量、肝旺症状(急躁易怒、好动多啼、咬齿磨牙等)积分和总积分比较,差异均无统计学意义(P>0.05),具有可比性。治疗后,2组食欲、食量、肝旺症状积分和总积分均显著下降,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组下降更显著(P<0.05)。治疗组总有效率为95.0%,对照组为77.5%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组胃电图正常和紊乱例数比较,差异无统计学意义(P>0.05),具有可比性。治疗后,2组胃电图恢复正常例数均明显增加,经统计学分析,差异有统计学意义(P<0.05或P<0.01),且治疗组恢复正常更明显(P<0.05)。结论调中饮治疗儿童厌食症脾虚肝旺证,不仅能明显改善患儿的症状积分,还能改善胃电节律,升高血清锌水平,降低VIP,临床疗效显著,值得临床推广应用。
Objective To observe Tiaozhong Yin(调中饮)on clinical efficacy of anorexia in children with asthenia of the spleen and effulgence of the liver syndrome and electrogastrogram,serum zinc and vasoactive intestinal peptide(VIP).Methods Eighty cases of anorexia in children with asthenia of the spleen and effulgence of the liver syndrome were divided into treatment group and control group according to random number table method,with 40 cases in each.The control group was given zinc gluconate granulate orally,while the treatment group was given Tiaozhong Yin orally.Four weeks constituted 1 course of treatment for both groups,and we kept statistics about the curative effects after 2 courses of treatment.Results Before treatment,the difference was not statistically significant in the scores of appetite,food intake,the effulgence of the liver symptoms(impetuosity and susceptibility to rage,hyperactivity and more crying,bite and grinding teeth etc.)and total score between the two groups(P>0.05),and they were comparable.After treatment,the scores of appetite,food intake,the effulgence of the liver symptoms and total score of the two groups all significantly decreased,and the difference was statistically significant compared with the same group before treatment(P<0.05),moreover,the treatment group decreased more significantly(P<0.05).The total effective rate of the treatment group was 95.0%,that of the control group was 77.5%,and the difference was statistically significant between the two groups(P<0.05).Before treatment,there was no significant difference in the number of normal and disordered cases of electrogastrogram between the two groups(P>0.05),and they were comparable.After treatment,the number of returning to normal cases of electrogastrogram increased significantly,and the difference was statistically significant(P<0.05 or P<0.01),moreover,the returning to normal of the treatment group was more significant(P<0.05).Conclusion It can not only significantly improve the symptom scores of the children patients,but als
作者
连俊兰
王海云
詹璐
邵征洋
LIAN Junlan;WANG Haiyun;ZHAN Lu;SHAO Zhengyang(Department of TCM,Zhejiang Integrated Chinese and Western Medicine Hospital,Hangzhou,Zhejiang,310018,China;Department of Pediatrics,Zhejiang Provincial Tongde Hospital,Hangzhou,Zhejiang,310053,China;Department of Pediatrics,Zhejiang Integrated Chinese and Western Medicine Hospital,Hangzhou,Zhejiang,310018,China)
出处
《中医儿科杂志》
2020年第1期42-46,共5页
Journal of Pediatrics of Traditional Chinese Medicine
基金
浙江省中医药科学计划项目(2017ZA106)。
关键词
厌食症
儿童
脾虚肝旺证
调中饮
胃电图
锌
血管活性肠肽
临床观察
anorexia
children
asthenia of the spleen and effulgence of the liver symptom
Tiaozhong Yin(调中饮)
electrogastrogram
zinc
vasoactive intestinal peptide(VIP)
clinical observation
