摘要
细菌的群体感应是目前环境生物技术领域研究的热点,细菌能够通过分泌的信号分子来对整个细菌群体功能进行调节与控制,不同种类的信号分子有着不同的调控系统,它们的组成、功能、调节途径都不一样。综述了群体感应中不同种类的信号分子各自的调控途径及机制,并详细介绍其中的酰基高丝氨酸内酯的种类、相应的调控方式,以及目前的研究手段与方法。同时介绍了利用调控信号分子酰基高丝氨酸内酯来对群体感应系统进行调控,用以解决混菌合成聚羟基脂肪酸酯工艺中问题的相关研究,最后对群体感应的相关研究进行了总结与展望。
The quorum sensing of bacteria is a hotspot in the field of environmental biotechnology. Bacteria can regulate and control the function of the whole bacterial population through the secreted signal molecules. Different kinds of signal molecules have different regulatory systems, and their composition, function, and adjustment methods are different. This paper reviewed the regulatory pathways and mechanisms of different types of signal molecules in quorum sensing, and introduced the types of acyl homoserine lactones in detail and the corresponding regulatory methods in use, as well as current research means and methods. The regulation of the quorum sensing system was carried out by using the regulatory signal molecule acyl homoserine lactone to solve the problems in the process of synthesizing polyhydroxyalkanoates. Finally, the related research on quorum sensing was summarized and prospected.
作者
刘少蛟
马广玉
温沁雪
李芳
陈志强
LIU Shao-jiao;MA Guang-yu;WEN Qin-xue;LI Fang;CHEN Zhi-qiang(School of Environment,Harbin Institute of Technology,Harbin 150090,China;Sino-Japan Friendship Center for Environmental Protection,Beijing 100029,China)
出处
《中国给水排水》
CAS
CSCD
北大核心
2019年第24期25-31,共7页
China Water & Wastewater
基金
国家自然科学基金资助项目(51578183)
国家重点研发计划项目(2016YFC0401102-3)
