摘要
目的:探讨无痛人工流产术中丙泊酚联合布托啡诺的镇痛效果及不良反应。方法:选取2015年5月—2018年5月本院收治的早孕行无痛人工流产术者2000例,按照随机数字表方法分组,对照组丙泊酚静脉输注,观察组在对照组基础上加用布托啡诺输注。观察两组术前术后心率、失血量以及手术时间,对比两组镇痛效果及不良反应。结果:观察组镇痛有效率(100.0%)高于对照组(84.2%)(P<0.05);术后观察组心率、MAP、SpO 2优于对照组,手术时间(2.6±0.9min)及手术出血量(11.1±4.4ml)低于对照组(4.6±0.6min、20.2±4.8ml),不良反应发生率(5.6%)低于对照组(14.2%)(均P<0.05)。结论:在早孕无痛人工流产过程中采用丙泊酚联合布托啡诺镇痛效果优于单用丙泊酚,具有经济、便捷等优点,值得临床应用。
Objective:To investigate the effect and adverse reaction of propofol combined with butorphanol used for painless artificial abortion.Methods:2000 women who underwent painless abortion were enrolled and were divided into two groups by the random number table from May to May 20,2015.The women in the control group were given intravenous propofol,and the women in the study group were given intravenous propofol combined with butorphanol.The heart rate before and after operation,blood loss volum during operation,and operation time of women in both groups were observed.The analgesic effect and adverse reaction of women were compared between the two groups.Results:The analgesic effective rate of women in the study was 100.0%,which was significant higher than that(84.2%)of women in the control group(P<0.05).The heart rate and values of MAP and SpO 2 of women in the study were significant better than those of of women in the control group(P<0.05).The operation time,the amount of bleeding during operation,and the incidence of adverse reaction of women in the study were 2.6±0.9min,11.1±4.4ml,and 5.6%,respectively,which were ignificant higher than those(4.6±0.6min,20.2±4.8ml,and 14.2%,respectively)of women in the control group(P<0.05).Conclusion:The efficacy of propofol combined with butorphanol used for painless artificial abortion is better than that of propofol used only,which has economic and convenient advantages,so it is worthy of application in clinical practice.
作者
袁蕾
王志萍
YUAN Lei;WANG Zhiping(Key Laboratory of Anesthesiology of Xuzhou Medical University,Xuzhou,Jiangsu Province,221009;The Second Hospital of Wuxi;Wuxi People's Hospital)
出处
《中国计划生育学杂志》
2020年第2期165-167,共3页
Chinese Journal of Family Planning
关键词
早孕
无痛人工流产
丙泊酚
布托啡诺
镇痛效果
不良反应
Early pregnancy
Painless induced abortion
Propofol
Butorphine
Analgesic effect
Adverse reaction
