摘要
目的:探究麻银汤对急性支气管炎患儿肺功能及炎性因子影响。方法:纳入我院2017年1月~2019年1月收治的100例急性支气管炎患儿为研究对象,根据治疗方法不同采取随机数字表法将患儿分为实验组与对照组,予以对照组患儿(50例)西药常规治疗,实验组患儿(50例)麻银汤治疗,对比、分析两组患儿临床治疗效果、治疗后患儿症状(发热、咳嗽、肺部啰音)缓解时间、治疗前后患儿中医症状积分变化情况、治疗前后患儿血清炎性因子水平变化情况及肺功能指标变化情况、不良反应等。结果:实验组患儿治疗总有效率(98.00%)高于对照组(86.00%),P<0.05;治疗后实验组患儿发热、咳嗽、肺部啰音等症状缓解时间短于对照组,P<0.05;治疗前,两组患儿中医症状积分、白介素-6(IL-6)、白介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)等血清炎性因子水平、第1s用力呼气容积(FEV1)、用力呼气流量(PEF)、第1s最大呼气量/用力肺活量(FEV1/FVC)等肺功能指标均相当,P>0.05,治疗后各组患儿中医症状积分、IL-6、IL-8、TNF-α、FEV1、PEF、FEV1/FVC指标均改善,实验组患儿指标改善优于对照组,P<0.05;实验组患儿不良反应发生率(0.00%)低于对照组患儿(10.00%),P<0.05。结论:麻银汤对急性支气管炎患儿具有积极影响,患儿临床疗效佳,炎性因子水平改善,肺功能改善,患儿病情好转,恢复快,未见不良反应,安全可靠,值得推广与应用。
Purpose :To explore the effect of mayin decoction on lung function and inflammatory factors in children with acute bronchitis.Methods:In our hospital from January 2017 to January 2019, 100 cases of children with acute bronchitis as the research object, according to different treatment to children with random number table method divided into experimental group and control group, to the control group(50 cases) in children with conventional western medicine treatment, the experimental group(50 cases) in children with MaYin soup treatment, comparison and analysis of two groups of children with clinical treatment, after treatment with symptoms(fever, cough, lung’s) relief time, before and after treatment with Chinese medicine symptom integral, before and after treatment, the changes of serum levels of inflammatory cytokines in children with changes and the changes of lung function index, adverse reactions, etc.Results:The total effective rate(98.00%) in the experimental group was higher than that in the control group(86.00%), P< 0.05. After treatment, the symptoms of fever, cough and lung rashes in the experimental group were relieved for shorter time than those in the control group(P< 0.05). Before the treatment, two groups of children with Chinese medicine symptom integral, interleukin 6(IL 6) and interleukin 8(IL-8), tumor necrosis factor alpha(TNF alpha), serum levels of inflammatory factors such as 1 s forced expiratory volume(FEV1) and forced expiratory flow(PEF), 1 s maximum volume/forced vital capacity(FEV1/FVC) such as pulmonary function indexes, P> 0.05, groups after treatment with Chinese medicine symptom integral, IL-6, IL-8, TNF alpha, FEV1, PEF and FEV1/FVC indexes to improve, The improvement of indicators in the experimental group was better than that in the control group(P< 0.05). The incidence of adverse reactions in the experimental group(0.00%) was lower than that in the control group(10.00%), P< 0.05.Conclusion:Ma Yin decoction has a positive effect on children with acute bronchitis, with good cl
作者
韦汉才
袁彬
WEI Hancai;YUAN Bin(Pediatrics,Zigong Hospital of Traditional Chinese medicine,Zigong Sichuan 64300,China)
出处
《四川中医》
2020年第1期97-100,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
四川省科技计划项目(编号:2012sz0131)
关键词
急性支气管炎患
中医治疗
肺功能
炎性因子
不良反应
Children with acute bronchitis
Curative effect
Lung function
Inflammatory factors
Adverse reactions
