摘要
目的探究胸部创伤合并肺损伤术后雾化吸入盐酸氨溴索注射液的效果及对肺部并发症发生情况的影响。方法选择2017年10月至2020年10月我院收治的100例胸部创伤合并肺损伤患者作为研究对象,将其随机分为常规组和研究组,各50例。常规组进行常规治疗及护理干预,研究组在常规组基础上雾化吸入盐酸氨溴索注射液。比较两组的肺损伤程度分级、机械通气情况、生命体征相关指标(T、WBC、PaO_(2)、PaCO_(2)、SaO_(2))及肺部并发症发生情况。结果治疗7 d后,研究组的肺损伤程度分级明显轻于常规组(P<0.05)。治疗7 d后,两组的机械通气患者占比明显低于治疗前,且研究组低于常规组(P<0.05)。治疗3、7 d后,两组的T、WBC、PaCO_(2)均较治疗前降低,PaO_(2)、SaO_(2)均较治疗前升高,且研究组优于常规组(P<0.05)。研究组的肺部并发症总发生率为26.00%,显著低于常规组的72.00%(P<0.05)。结论胸部创伤合并肺损伤术后雾化吸入盐酸氨溴索注射液能够有效减轻患者的肺损伤程度,降低机械通气患者占比,改善生命体征相关指标,降低肺部并发症发生率。
Objective To explore the effect of atomization inhalation of ambroxol hydrochloride injection after thoracic trauma complicated with lung injury and its influence on occurrence of pulmonary complications.Methods One hundred patients with thoracic trauma complicated with lung injury treated in our hospital from October 2017 to October 2020 were selected as the research objects,and the patients were randomly divided into routine group and study group,with 50 cases in each group.The routine group received routine treatment and nursing intervention,and the study group received atomization inhalation of ambroxol hydrochloride injection on the basis of the routine group.The grade of lung injury degree,the mechanical ventilation situation,vital signs related indexes(T,WBC,PaO_(2),PaCO_(2),SaO_(2))and the incidence of pulmonary complications were compared between the two groups.Results After 7 d of treatment,the grade of lung injury degree in the study group was significantly lighter than that in the routine group(P<0.05).After 7 d of treatment,the proportion of patients with mechanical ventilation in the two groups was significantly lower than that before treatment,and that in the study group was lower than the routine group(P<0.05).After 3 and 7 d of treatment,T,WBC and PaCO_(2) in the two groups were lower than those before treatment,PaO_(2) and SaO_(2) were higher than those before treatment,and those in the study group were better than the routine group(P<0.05).The total incidence of pulmonary complications in the study group was 26.00%,which was significantly lower than 72.00%in the routine group(P<0.05).Conclusion Atomization inhalation of ambroxol hydrochloride injection after thoracic trauma complicated with lung injury can effectively reduce the degree of lung injury,reduce the proportion of patients with mechanical ventilation,ameliorate the vital signs retated indexes,and reduce the incidence of pulomonary complications.
作者
石维超
高琳英
SHI Weichao;GAO Linying(the Second Affiliated Hospital of Xi'an Medical University,Xi'an 710038,China)
出处
《临床医学研究与实践》
2022年第2期35-38,共4页
Clinical Research and Practice
关键词
胸部创伤合并肺损伤
雾化吸入
盐酸氨溴索注射液
肺损伤程度
肺部并发症
thoracic trauma complicated with lung injury
atomization inhalation
ambroxol hydrochloride injection
degree of lung trauma
pulomonary complications
