摘要
目的探讨尤瑞克林联合血栓通对急性缺血性脑梗死(Acute Ischemic Stroke,AIS)患者的临床效果及对患者神经功能缺损评分变化与日常生活能力的影响。方法按随机抽样法选取2017年6月~2019年1月于我院就诊的114例CIS患者为研究对象,按随机数字表法将其分为观察组和对照组,各57例。两组入组前均给予基础性治疗,对照组常规治疗基础上以尤瑞克林进行治疗,而观察组则在对照组的基础上联合使用血栓通,对比两组疗效以及患者治疗前后的神经功能缺损和日常生活能力的变化情况。结果两组治疗前NIHSS评分对比无显著差异(P>0.05);观察组治疗1疗程后以及治疗完毕NIHSS评分低于对照组(P<0.05);观察组治疗总有效率高于对照组(P<0.05);治疗前两组SF-36评分差异无统计学意义(P>0.05);治疗后观察组SF-36各项评分均高于对照组(P<0.05)。结论在CIS患者中采用尤瑞克林联合血栓通治疗可以提高临床治疗效果,改善患者神经功能缺损以及恢复患者日常生活能力,值得应用。
Objective To investigate the clinical effects of Ureklin combined with Xueshuantong on patients with acute ischemic cerebral infarction(AIS)and the changes of neurological deficit scores and daily living ability.Methods A total of 114 CIS patients who were admitted to our hospital from June 2017 to January 2019 were randomly selected according to the random sampling method.They were divided into observation group and control group according to the random number table method,57 cases each.The two groups were given basic treatment before enrollment,and the control group was treated with uricillin on the basis of routine treatment,while the observation group was combined with thrombus on the basis of the control group.The efficacy of the two groups and the nerves before and after treatment were compared.Changes in functional impairment and daily living ability.Results There was no significant difference in NIHSS score between the two groups before treatment(P>0.05).The NIHSS score of the observation group was lower than that of the control group after one course of treatment and after finishing treatment(P<0.05).The total effective rate of the observation group was higher than the control group(P<0.05).There was no significant difference in SF-36 scores between the two groups before treatment(P>0.05).After treatment,SF-36 scores in observation group were higher than those in control group(P<0.05).Conclusion The treatment of Urekrin combined with Xueshuantong in CIS patients can improve the clinical therapeutic effect,improve the neurological deficit and restore the daily living ability of patients,which is worthy of application.
作者
黄德波
冯国宽
毛献泉
何玉燕
周远方
HUANG Debo;FENG Guokuan;MAO Xianquan(Hezhou People's Hospital,Hezhou 542899,China)
出处
《国际精神病学杂志》
2019年第6期1063-1066,共4页
Journal Of International Psychiatry
基金
2018年度第一批贺州市科学研究与技术开发计划(经费)项目，项目名称：TREVO取栓支架与静脉溶栓治疗急性大动脉闭塞性脑梗死疗效对比(编号：贺科转201808039)
关键词
尤瑞克林
血栓通
急性缺血性脑梗死
神经功能缺损
日常生活能力
Ureklin
Xueshuantong
Acute ischemic cerebral infarction
Neurological impairment
Activity of daily living
