摘要
目的探讨血清同型半胱氨酸及D-二聚体在消化系统肿瘤中的表达及临床价值。方法选取消化系统肿瘤患者50例作为研究对象,并选取同期健康体检者30例作为对照组,检测两组血清同型半胱氨酸及D-二聚体的水平、检测不同消化系统肿瘤患者的血清同型半胱氨酸及D-二聚体水平、检测消化系统肿瘤患者不同病期和病情的血清同型半胱氨酸及D-二聚体水平,并计算消化系统肿瘤患者血清同型半胱氨酸及D-二聚体水平与DAI评分、CPB的相关性。结果研究组患者的血清同型半胱氨酸及D-二聚体水平显著高于对照组(P<0.05);研究组内不同肿瘤类型患者的血清同型半胱氨酸及D-二聚体水平无明显的统计学差异(P>0.05);研究组中,重度患者的血清同型半胱氨酸及D-二聚体水平最高,明显高于轻度患者和中度患者(P<0.05);研究组患者血清同型半胱氨酸及D-二聚体水平与DAI评分、CPB有明显的相关性,且为正相关。结论消化系统肿瘤患者血清同型半胱氨酸及D-二聚体水平可作为判断消化系统肿瘤病情严重程度的重要参考指标,具有极好的临床诊断价值。
Objective To investigate the expression and clinical value of serum homocysteine and D-dimer in digestive system tumors.Methods 50 patients with digestive system tumors were selected as the research subjects,and 30 healthy subjects who were examined at the same period were selected as the control group.Serum homocysteine and D-dimer level,serum homocysteine and D-dimer level in patients with different digestive system tumors,serum homocysteine and D-dimer level in patients with digestive system tumors at different stages and conditions were detected,and to calculate the correlation between serum homocysteine and D-dimer levels and DAI score and CPB in patients with digestive system tumors.Results The levels of serum homocysteine and D-dimer in the study group were significantly higher than those of the control group(P<0.05).The levels of serum homocysteine and D-dimer in patients with different tumor types in the study group were not.The statistical difference was significant(P>0.05).In the study group,the serum homocysteine and D-dimer levels were the highest in the severe patients,which was significantly higher than that in the mild and moderate patients(P<0.05).Serum homocysteine and D-dimer levels were significantly correlated with DAI score and CPB,and were positively correlated.Conclusion Serum homocysteine and D-dimer levels in patients with digestive system tumors can be used as an important reference for judging the severity of digestive system tumors,and have excellent clinical diagnostic value.
作者
贾红云
卢坤
JIA Hongyun;LU Kun(Zhoukou Central Hospital,Zhoukou,466000)
出处
《实用癌症杂志》
2020年第2期182-184,195,共4页
The Practical Journal of Cancer
基金
2018年河南省科技攻关项目(编号:172102310075)
