摘要
黄芪是常用的补气类中药,是典型的多效中药。临床上以黄芪为君药的复方不胜枚举,功效十分广泛,仅目前《中国药典》中收载的含黄芪的复方就有200多种。然而,现行的质量评价方法难以准确判断黄芪药材的优劣,更无法有效关联黄芪在不同复方配伍环境中的定向功效。鉴于黄芪药材的多效性,急需新的技术与思路,构建符合中医药辩证论治观的质量评价体系。综述目前黄芪药材质量评价的研究进展,并从质量标志物的寻找策略出发提出关于黄芪质量评价的新的见解和策略。
Astragali Radix is a common traditional Chinese medicine for tonifying qi, which is a typical multi-effect Chinese medicine. Clinically, there are many formulas take Astragali Radix as one principal drug, and exert extensive pharmacological efficacies. At present, there are more than 200 kinds of formulas containing Astragali Radix contained in the Chinese Pharmacopoeia Commission. However, the current quality evaluation of Astragali Radix is difficult to evaluate its effectiveness relevant to its oriented pharmacodynamic action associated with the compatible environment in formulas under the particular pathologic conditions. Thus, a novel approach is urgently needed to construct a quality evaluation system that conforms to the dialectical view of Chinese medicine. This paper reviews the current research progress of the quality evaluation of Astragali Radix and proposes new insights and strategies.
作者
薛倩倩
李爱平
李科
刘月涛
秦雪梅
XUE Qianqian;LI Aiping;LI Ke;LIU Yuetao;QIN Xuemei(Modem Research Center for Traditional Chinese Medicine,Shanxi University,Taiyuan 030006,China;Shanxi University Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province,Taiyuan 030006,China)
出处
《药物评价研究》
CAS
2019年第12期2459-2463,共5页
Drug Evaluation Research
基金
国家自然科学基金资助项目(31770362
81703697)
关键词
黄芪
质量评价
定向药效成分
质量标志物
Astragali Radix
quality evaluation
directional medicinal components
quality marker
