摘要
目的探讨早期促醒康复干预对重症病毒性脑炎伴植物状态病儿临床预后的影响。方法选取陕西省榆林市儿童医2014年8月至2017年12月收治重症病毒性脑炎伴植物状态病儿共127例,其中生命体征稳定出院但机体功能4周内未完全恢复、后再行促醒康复干预共71例设为对照组,生命体征稳定后直接行促醒康复干预共56例设为观察组,比较两组治疗前后植物状态分级、植物状态评分、脑电图评分、脑干诱发电位评分、随访GFMF评分及随访韦氏评分。结果观察组治疗后1个月、3个月植物状态评分[(473.71±70.16)分,(523.70±61.26)分]、脑电图评分[(4.51±1.10)分,(4.93±1.36)分]及脑干诱发电位评分[(4.93±1.36)分,(3.80±1.02)分]均显著高于治疗后对照组[(3.60±0.81)分,(1.32±0.40)分];[(4.05±0.94)分,(2.41±0.67)分];[(4.20±1.01)分,(3.12±0.85)分]、治疗前观察组[(326.53±30.34)分,(473.71±70.16)分,(523.70±61.26)分](P<0.05);同时观察组随访3个月、9个月的GFMF评分[(6.75±1.38)分,(78.59±6.50)分]和韦氏评分[(51.43±5.90)分,(98.63±16.28)分]均显著高于对照组[(6.08±1.44)分,(62.43±5.06)分;(48.38±5.67)分,(85.06±12.05)分](P<0.05)。结论早期促醒康复干预用于重症病毒性脑炎伴植物状态病儿可有效改善意识状态,提高肢体活动功能,并有助于促进认知水平恢复。
Objective To investigate the influence of early awakening rehabilitation intervention on clinical prognosis of children with severe viral encephalitis accompanied by vegetative state.Methods 127 children with severe viral encephalitis accompanied by vegetative state were chosen in Yulin children's Hospital of Shaanxi in the period from Auguste 2014 to December 2017 and di⁃vided into two groups including control group(71 children)with awakening rehabilitation intervention which discharged with sta⁃ble vital signs while incomplete recovery within 4 weeks and observation group(56 children)with early awakening rehabilitation interventiondirectly after stable vital signs.The vegetation status grading,vegetation status score,electroencephalogram score and brainstem evoked potential score before and after treatment,GFMF score and Wechsler score with follow⁃up of both groups were compared.Results The vegetation status grading of obseruation group after treatment were significant better than control group and before treatment(P<0.05).The plant status score[(473.71±70.16)points,(523.70±61.26)points],electroencephalogram score[(4.51±1.10)points,(4.93±1.36)points]and brainstem evoked potential score[(4.93±1.36)points,(3.80±1.02)points]of observa⁃tion group after treatment were significant more than control group after treatment[(3.60±0.81)points,(1.32±0.40)points];[(4.05±0.94)points,(2.41±0.67)points];[(4.20±1.01)points,(3.12±0.85)points]and observation group before treatment[(326.53±30.34)points,(473.71±70.16)points,(523.70±61.26)points](P<0.05).The GFMF score and Wechsler score with follow⁃up of observation group with follow⁃up were significant higher than control group[(6.08±1.44)points,(62.43±5.06)points;(48.38±5.67)points,(85.06±12.05)points](P<0.05).Conclusion Early awakening rehabilitation intervention in the treatment of children with severe viral encephalitis accompanied by vegetative state can efficiently improve the consciousness state,higher the limb movement func⁃tion and promote
作者
苏慧霞
陈艳
杨欣
SU Huixia;CHEN Yan;YANG Xin(Department of Pediatrics,Yulin childrens Hospital of Shaanxi,Yulin,Shaanxi 719000,China;Department of critical medicine,Yulin childrens Hospital of Shaanxi,Yulin,Shaanxi 719000,China)
出处
《安徽医药》
CAS
2020年第1期20-23,共4页
Anhui Medical and Pharmaceutical Journal
关键词
脑炎
病毒性
持续植物人状态
诱发电位
脑电描记术
电刺激疗法
运动疗法
音乐疗法
认知疗法
治疗结果
康复
儿童
早期促醒
Encephalitis
viral
Persistent vegetative state
Evoked potentials
Electroencephalography
Electric stimulation therapy
Exercise therapy
Music therapy
Cognitive therapy
Treatment outcome
Rehabilitation
Child
Early awakening
