摘要
目的:探讨血府逐瘀汤对高脂血症患者血脂水平及血液流变学指标的影响。方法:将155例患者随机分为观察组77例对照组78例。对照组口服辛伐他汀,10mg/次,1次/d,晚餐后0.5小时温水送服;观察组在对照组治疗的基础上口服血府逐瘀汤,1剂/d水煎分服。2组均持续治疗3个月。比较2组治疗前后血脂水平、血液流变学指标、颈动脉血流量变化及不良反应发生率。结果血脂指标、血流流变学指标及颈动脉血流量治疗前2组比较差异无统计学意义(P> 0.05),治疗后2组均较治疗前显著改善,差异有统计学意义(P<0.05),且2组间比较差异也有统计学意义(P<0.05)。不良反应发生率2组比较差异无统计学意义(P> 0.05)。结论:血府逐瘀汤有助于改善高脂血症患者血脂水平及血液流变学指标,增加颈动脉血流量且不增加不良反应。
Objective:To explore the effects of Xuefu Zhuyu decoction on blood lipid levels and hemorheological indexes of the patients with hyperlipemia.Methods:All 155 patients were randomized into 77 cases of the observation group and 78 cases of the control group,the control group took simvastatin,10 mg each time,once each day,taking with warm water in half an hour after the supper.The observation group took Xuefu Zhuyu decoction based on the therapy the control group accepted,one dose each day,water decocted and taking twice.Both groups were treated for three months consecutively.To compare blood lipid level,hemorheological indexes,carotid blood flow(CBF) variation and adverse reaction incidence between both groups before and after treating.Results:The difference had no statistical meaning in the indexes of blood lipid,hemorheological indexes and CBF between both groups before treating(P>0.05),both groups have been improved after treating compared with before treating,and the difference had statistical meaning(P<0.05),and the difference had statistical meaning between both groups after treating(P<0.05).The difference had no statistical meaning in the incidences of adverse reaction between both groups(P>0.05).Conclusion:Xuefu Zhuyu decoction is helpful to improve blood lipid level and hemorheological indexes of the patients with hyperlipemia,increase CBF and won’t increase adverse reaction.
作者
闫捷
贾海龙
YAN Jie;JIA Hailong(Functional Staff Room,Qibo Medical College,Longdong University,Qingyang 745000,China;Qingyang City TCM Hospital)
出处
《西部中医药》
2019年第10期47-49,共3页
Western Journal of Traditional Chinese Medicine
关键词
高脂血症
血府逐瘀汤
血脂水平
血液流变学
血流量
不良反应
hyperlipemia
Xuefu Zhuyu decoction
blood lipid level
hemorheology
blood flow
adverse reaction
