摘要
茶多酚是茶叶中多酚类物质的总称,是茶叶中有药理和保健功能的主要成分之一。神经退行性疾病是一种高发疾病,严重影响人类健康水平和生活质量。近年来,茶多酚对神经退行性疾病的保护作用及其机制研究较为迅速,它能够清除自由基,降低脂质过氧化,减少DNA氧化破坏,螯合铁离子,提高神经元细胞存活率,降低缺血再灌注损伤中的梗死面积等,从而起到保护神经元的作用。本文就茶多酚对主要神经退行性疾病的相关研究进展进行综述。
Tea polyphenols is the general name of polyphenols in tea and is one of the constituents with pharmacological and healthy functions in tea.Neurodegenerative diseases is a high incidence of disease,serious impact on human health and quality of life.In recent years,the role and mechanism of tea polyphenols on neurodegenerative diseases research relatively quickly.Tea polyphenols can scavenge free radicals,reduce lipid peroxidation,reduce DNA oxidative damage,chelate iron ions,increase neuronal cell survival,and reduce infarct size during ischemia-reperfusion injury,thereby protecting neurons.In this paper,we reviewed the research progress of tea polyphenols on major neurodegenerative diseases.
作者
李梅
尚宇梅
王智慧
潘朦
李娇阳
任海涛
LI Mei;SHANG Yu-mei;WANG Zhi-hui;PAN Meng;LI Jiao-yang;REN Hai-tao(West Yunnan University of Applied Sciences College of Tea(Pu’Er),Yunnan,Puer 665000,China)
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2019年第11期1631-1634,共4页
JOURNAL OF BASIC CHINESE MEDICINE
关键词
茶多酚
神经退行性疾病
机制
保护作用
Tea polyphenols
Neurodegenerative diseases
Mechanism
Protective effect
