摘要
目的包虫病是WHO认定的全球十种经济负担最重的疾病之一,中国又是全球包虫病流行最为严重的国家之一。本文采用系统评价方法评价中国包虫病患者的经济负担。方法计算机检索Web of Science、PubMed、CNKI、WanFang Data和VIP数据库,收集有关中国包虫病患者经济负担的研究,检索时限均从2008年1月1日至2018年12月31日。由2名研究员独立筛选文献、提取资料和评价纳入研究偏倚风险后,采用Excel2013软件进行数据录入和统计分析。结果最终纳入27篇文献,分析结果显示:2008年至2018年间,包虫病患者平均住院费用约21 201.85元。其中,囊型包虫病患者平均住院费用约为13 817.21元,泡型包虫病患者平均住院费用约为39 880.72元,且平均住院费用呈现逐年增长的趋势。包虫病患者平均年龄范围为8.6岁~59.21岁,平均住院天数为17.12天。患者年龄、住院天数、有无医疗保险、治疗转归对患者经济负担有影响。结论我国包虫病患者平均住院费用总体呈上升趋势,经济负担较重。受纳入研究数量和质量的限制,上述结论尚待更多高质量研究予以验证。
Objectives Echinococcosis is one of the 10 most economically burdened diseases recognized by WHO in the world, and China has the highest prevalence of echinococcosis. Thus, the present study was conducted to systematically review the economic burden of echinococcosis in Chinese population. Methods Databases including Web of Science, PubMed, CNKI, WanFang Data and VIP were electronically searched from January 1st, 2008 to December 31st,2018 to collect studies on the economic burden of echinococcosis in China. Two reviewers independently screened literature, extracted data, and assessed risk of bias of included studies. Excel 2013 software was used for data entry and statistical analysis. Results A total of 27 studies were included. The analysis showed that the average cost of echinococcosis was approximately 21 201.85 yuan. The average cost of cystic echinococcosis was approximately 13817.21 yuan. The average cost of alveolar echinococcosis was approximately 39 880.72 yuan. The average hospitalization cost of echinococcosis generally tended to rise from 2008 to 2018. The average age of patients ranged from 8.6 to 59.21 years, with the average length of stay in hospital was 17.12 days. Many of the included studies showed that patients’ age, length of hospital stay, medical insurance, and therapeutic outcomes have an impact on the economic burden of echinococcosis. Conclusions The average hospitalization cost of patients with echinococcosis in China is high and shows an upward trend. Due to limited quality and quantity of the included studies, more high quality studies are required to verify above conclusions.
作者
艾力亚力·艾力
孙立
李波霖
温浩
Ailiyali.AILI;SUN Li;LI Bolin;WEN Hao(School of Public Health,Xinjiang Medical University,Urumqi 830011,P.R.China;State Key Laboratory of High Risk of Diseases and Prevention in Central Asia,Urumqi 830054,P.R.China)
出处
《中国循证医学杂志》
CSCD
北大核心
2019年第12期1416-1422,共7页
Chinese Journal of Evidence-based Medicine
基金
新疆维吾尔自治区重点实验室专项项目（编号：2014KL002）
教育部“长江学者创新团队发展计划”项目（编号：IRT1181）
关键词
包虫病
经济负担
系统评价
中国
Echinococcosis
Economic burden
Systematic review
China
