摘要
从罗汉松内生真菌Pestalotiopsis heterocornis的发酵培养液中分离得到10个代谢产物,应用质谱、核磁共振等现代波谱学方法鉴定为jesterone(1),hydroxy-jesterone(2),ambuic acid(3),6β-羟基-豆甾-4-烯-3-酮(4),(24 S)-麦角甾-5-烯-3β,7α-二醇(5),7,22-二烯-3β,5α,7β-三羟基-麦角甾醇(6),麦角甾-7,22-二烯-3-酮(7),(4 E,8 E,2 S,3 R,2′R)-N-2′-羟基棕榈酰-9-甲基-4,8-sphingadienin(8),鲨肝醇(9),棕榈酸(10)。以上化合物均为首次从内生真菌P.heterocornis的代谢产物中分离得到,化合物4,6,7为首次从拟盘多毛孢属真菌代谢产物中分离得到。
Ten compounds were isolated and identified from endophytic fungi Pestalotiopsis heterocornis,isolated from Podocarpus macrophyllus,which collected in Hangzhou,China.Their structures were elucidated on the basis of spectroscopic data as jesterone(1),hydroxy-jesterone(2),ambuic acid(3),6β-Hydroxystigmast-4-en-3-one(4),(24 S)-ergosta-5-en-3β,7α-diol(5),ergosta-7,22-dien-3β,5α,7β-triol(6),ergosta-7,22-dien-3-one(7),(4 E,8 E,2 S,3 R,2′R)-N-2′-hydroxyhexadecanoyl-9-methyl-4,8-sphingadienin(8),batyl alcohol(9),palmitic acid(10).All compounds were isolated from P.heterocornis for the first time,and compounds 4,6,7 were obtained for the first time from Pestalotiopsis spp.
作者
鲍真真
吴洁
王奎武
吴斌
钟嫄
BAO Zhenzhen;WU Jie;WANG Kuiwu;WU Bin;ZHONG Yuan(School of Pharmacy,Jiangsu Health Vocational College,Nanjing 211800,China;School of Food Science and Biotechnology,Zhejiang Gongshang University,Hangzhou 310035,China;Ocean College,Zhejiang University,Zhoushan 530005,Zhejiang,China)
出处
《广西植物》
CAS
CSCD
北大核心
2019年第11期1568-1572,共5页
Guihaia
基金
国家自然科学基金面上项目(81573306)
江苏省“六大人才高峰”项目(2015-XCL-036)
江苏省青蓝工程优秀教学团队
江苏省高等学校自然科学研究项目(19KJD430005)
江苏省高等职业教育青年教师企业实践(2019QYSJPX171)~~
