摘要
背景:腱病是运动医学和康复领域的研究热点,但现有的研究长期以来在概念、机制及病理分期等方面存在着诸多争论。目的:对腱病相关的概念、炎症在腱病发生中的作用以及腱病的病理机制等问题进行系统的回顾与总结。方法:检索中国期刊网全文数据库(中国知网CNKI)、维普数据库、中国生物医学文献数据库(CBM)、中国医药学位论文全文数据库(万方)及PubMed数据库和Embase医药数据库,从腱病、腱止点、炎症、病理机制等几方面入手,检索了1990年以来一些相关的研究成果并进行了综述。结果与结论:对腱病概念的争论是建立在对其内部病理机制理解的基础之上的,而对腱病内部病理机制的理解将随着更多高质量研究的出现而不断被完善。对于腱病与炎症、腱病与负荷方式以及腱止点相关力学特点方面的研究将是以后值得关注的方向。
BACKGROUND:Tendinopathy is a hotspot in the fields of sports medicine and rehabilitation,but there have been many controversies about the concept,mechanism and pathological stages of tendinopathy for a long time.OBJECTIVE:To systematically review and summarize the related concepts of tendinopathy,the role of inflammation in the occurrence of tendinopathy and the pathological mechanism of tendinopathy.METHODS:CNKI,VIP,CBM,WanFang,PubMed and Embase databases were searched.From the aspects of tendinopathy,enthesis,inflammation and pathological mechanism,some related research results since 1990 were retrieved and summarized.RESULTS AND CONCLUSION:The results show that the debate on the concept of tendinopathy is based on the understanding of its pathological mechanism,and the understanding of the pathological mechanism of tendinopathy will continue to be improved with the emergence of more high-quality researches.The research on the relationship between tendinopathy and inflammation,the relationship between tendinopathy and load patterns,and the mechanical characteristics of enthesis will be a future focus.
作者
刘春雨
韩小燕
王琳
Liu Chunyu;Han Xiaoyan;Wang Lin(Beijing Sport University,Beijing 100084,China;School of Physical Education and Health,Yulin 537000,Guangxi Zhuang Autonomous Region,China)
出处
《中国组织工程研究》
CAS
北大核心
2020年第2期282-288,共7页
Chinese Journal of Tissue Engineering Research
关键词
腱病
腱止点
微细结构
细胞外基质
炎症
退化
概念
病理机制
tendinopathy
enthesis
microstructure
extracellular matrix
inflammation
degradation
concept
pathological mechanism
