摘要
通过分析古今治疗乳癖用药品味范围,为治疗乳癖选择用药提供参考.选取古今医家治疗乳癖文献所载医案临证处方,运用方剂计量学方法分析古代和现代用药范围、序列、相似度、差异性等.共统计58首古代医家治疗乳癖临证处方,宋金元时期27首,运用57味药;明清时期31首,用药59味.统计现代治疗乳癖临证处方44首,共用药109味.宋金元使用木香、大黄、轻粉、人参、巴豆、槟榔、枳壳、朱砂较多,明清时期大黄、木香、三棱、牵牛子、轻粉、枳壳应用较频繁;现代以柴胡、香附、当归、白芍使用最多,3个时期用药品味各有异同,宋金元与明清较为接近,其用药相似度指数较大(S=0.400),而现代用药已与古代出入较多,相似度指数很小(S=0.088和S=0.094).古今均用药品得22味;古用今不用药品得48味;今用古不用药品得85味.发现古代用药中有毒、峻烈、泻下、寒凉药品,现代已不再使用;而古代所用药品中平和、温通、和解、散结者,大多归入足厥阴、少阳和足阳明胃经用药,在现代仍使用;同时,现代在古代基础上新增药品较多,而以活血化瘀、通经活络、解毒化癥、散结消痰、温阳益肾药品为主.通过对比分析古今文献总结诸多医家治疗乳癖用药经验,可为乳癖治疗提供有效参考,其方剂计量学方法亦可成为其他疾病辨证论治经验研究的借鉴.
To analyze the scope of prescription taste in the treatment of milk addiction in ancient and modern eras in order to provide a reference for selection of drugs in the treatment of milk addiction in future.The literatures on clinical prescriptions of ancient and modern medical experts for the treatment of mammitis and milk addiction were reviewed and selected,and the scope,sequence,similarity and difference between the ancient and modern medicines were analyzed by prescription metrology.Of totally 58 prescriptions for the treatment of milk addiction in ancient times,there were 27 prescriptions and 57 drugs were used for the treatment of milk addiction in the Song,Jin and Yuan Dynasties;in Ming and Qing Dynasties,31 prescriptions,59 drugs were applied.In the modern treatment of milk addiction,44 clinical prescriptions and a total of 109 drugs were used.In Song,Jin and Yuan Dynasties saussurea,rhubarb,light powder,ginseng,croton,betel nut,fructus aurantii and cinnabarn were used commonly;in Ming and Qing Dynasties,rhubarb,saussurea,rhizome sparganii,semen pharbitidis,light powder and fructus aurantii were applied frequently;in modern times,bupleurum root,rhizome cyperi,angelica root and white peony root have been commonly used;there were similarities and differences in using medicine tastes among the 3 periods,the tastes in Song,Jin and Yuan Dynasties were more relatively approximate to those in Ming and Qing Dynasties,and the medicine similarity index between the 2 periods was large(S=0.400),while the similarity index between the taste of modern medicine and that of the ancient was small(S=0.088 and S=0.094),showing more differences were present.There were 22 drugs were used both in ancient and modern eras;the number of drugs used in ancient time but not applied in modern time was 48;the number of drugs applied at present but not used in the ancient time was 85.The drugs with toxicity,very strong action,cathartic and cold characteristics used in ancient times are no longer applied in modern times,while those drugs
作者
王苗
王萌
周铭心
Wang Miao;Wang Meng;Zhou Mingxin(The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,Xinjiang Uygur Autonomous Region,China;College of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi 830000,Xinjiang Uygur Autonomous Region,China)
出处
《中国中西医结合急救杂志》
CAS
CSCD
北大核心
2019年第4期490-493,共4页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
国家自然科学基金(30660219)
周铭心全国名中医传承工作室.
关键词
乳癖
用药范围
用药相似度
用药差异
方剂计量学
Milk addiction
Scope of drug use
Drug similarity
Drug differences
Prescription metrology
