摘要
目的分析氟哌塞吨美利曲辛片治疗功能性胃肠病伴焦虑抑郁障碍的临床治疗效果。方法选择该院自2017年1月—2019年1月期间功能性胃肠病伴焦虑抑郁障碍患者100例,利用奇偶数分组法将其分成参照组与观察组,每组50例,其中参照组使用雷贝拉唑、莫沙比利、匹维溴铵对患者进行治疗,观察组在参照组方法的基础上予以患者氟哌塞吨美利曲辛片进行治疗,观察并对比两组患者的治疗效果以及焦虑抑郁评分。结果观察组患者治疗后的焦虑与抑郁评分为(13.01±2.14)分与(12.11±3.25)分,明显优于治疗前的(19.09±4.13)分与(18.72±3.99)分,差异有统计学意义(t=9.24、9.08,P=0.00、0.00);且观察组治疗后的焦虑与抑郁评分明显优于参照组的(16.91±1.95)分与(16.61±2.17)分,差异有统计学意义(t=9.55、8.14,P=0.00、0.00);且观察组患者治疗后其总有效率为92.0%,参照组患者治疗后的总有效率为72.0%,两组数据差异有统计学意义(P<0.05)。结论氟哌塞吨美利曲辛片能够明显改善功能性胃肠病伴焦虑抑郁障碍患者的临床症状,提高患者的生活质量,临床应用价值显著,值得推广使用。
Objective To analyze the clinical therapeutic effect of fluphene citrate melitraceine in the treatment of functional gastrointestinal diseases with anxiety and depression. Methods One hundred patients with functional gastrointestinal disease and anxiety and depression were enrolled in our hospital from January 2017 to January 2019. They were divided into reference group and observation group by parity grouping method, 50 cases in each group. The patients were treated with rabeprazole, mosapride and pivaviron. The patients in the observation group were treated with the patient with norfloxacin on the basis of the reference group method. The two groups were observed and compared. Therapeutic effects as well as anxiety and depression scores. Results The anxiety and depression scores of the observation group were (13.01±2.14)points and (12.11±3.25)points, which were significantly better than those before treatment (19.09±4.13)points and (18.72±3.99)points, and the difference was significant (t=9.24,9.08,P=0.00,0.00);and the anxiety and depression scores of the observation group after treatment were significantly better than those of the reference group (16.91±1.95)points and (16.61±2.17)points, the difference was statistically significant(t=9.55,8.14,P= 0.00,0.00);and the total effective rate was 92.0% in the observation group after treatment, and the total effective rate after treatment in the reference group was 72.0%. The difference between the two groups was statistically significant(P< 0.05). Conclusion Fluezone tomexrel can significantly improve the clinical symptoms of patients with functional gastrointestinal disease and anxiety and depression, improve the quality of life of patients, and has significant clinical application value. It is worthy of popularization.
作者
张蓓
ZHANG Bei(Department of Gastroenterology, Shanghai Electric Power Hospital, Shanghai, 202157 China)
出处
《系统医学》
2019年第17期64-66,共3页
Systems Medicine
关键词
氟哌塞吨美利曲辛片
功能性胃肠病
焦虑抑郁障碍
疗效
Fluphene citrate melitracen tablets
Functional gastrointestinal disease
Anxiety and depression
Efficacy
