摘要
目的比较非体外循环冠脉旁路移植术(off-pump coronary artery bypass grafting,OP-CABG)后静脉泵注右美托咪定和丙泊酚的效果。方法随机将120例行OP-CABG的患者分为2组,各60例。研究组术后静脉泵注右美托咪定0.2~0.5μg/(kg·h),对照组静脉泵注丙泊酚1~3 mg/(kg·h)。2组均持续给药12 h。回顾性分析患者的临床资料。结果2组患者术后ICU留住时间、机械通气时间及SpO2、体温、心率、VAS评分、低SBP和5 d内谵妄发生率比较,差异均无统计学意义(P>0.05)。研究组患者的睡眠评分优于对照组,差异有统计学意义(P<0.05)。结论右美托咪定可显著改善不停跳OP-CABG患者术后的睡眠质量,而且不影响术后镇痛及谵妄的发生率。
Objective To compare the effects of dexmetomide and propofol by intravenous pump after off-pump coronary artery bypass grafting(off-pump coronary artery bypass grafting,OP-CABG).Methods Patients with 120 routine OP-CABG were randomLy divided into 2 groups,60 in each group.postoperative dexmedetomidine was injected with dexmedetomidine from 0.2 to 0.5μg/(kg·h)and propofol from the control group from 1 to 3 mg/(kg·h).All of the two groups were administered for 12 h.retrospectively analyze of patient clinical data.Results There was no significant difference in ICU retention time,mechanical ventilation time,SpO2,body temperature,heart rate,VAS score,low SBP and delirium incidence between the two groups(P>0.05).The sleep score of the patients in the study group was better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Dexmetomidine can significantly improve the sleep quality of patients after non-extracorporeal circulation coronary bypass surgery,and has no significant influence on postoperative analgesia and delirium.
作者
梅魁魁
赵文增
文冰
李红卫
赵国昌
Mei Kuikui;Zhao Wenzeng;Wen Bing;Li Hongwei;Zhao Guochang(Cardiovascular surgery,The First affiliated hospitalof Zhengzhou University,Zhengzhou 450052,China)
出处
《河南外科学杂志》
2019年第5期24-27,共4页
Henan Journal of Surgery
关键词
冠状动脉旁路移植术
右美托咪定
丙泊酚
Dexmetomidine
Postoperative delirium
Coronary artery bypass grafting
Propofol
