摘要
目的观察右美托咪定用于急性脑出血手术治疗的应用效果。方法将医院收治的80例急性脑出血手术治疗患者随机分为两组,各40例,对照组采用常规全麻方式,试验组在常规全麻方式的基础上加用右美托咪定,分别观察两组麻醉前、麻醉诱导后、气管插管后5 min、术中60 min和术毕时带管自主呼吸时的心率(HR)和平均动脉压(MAP),并比较两组术中丙泊酚和乌拉地尔用量。结果急性脑出血患者经麻醉后,在麻醉诱导后、气管插管后5 min、术中60 min和术毕时,试验组带管自主呼吸时HR和MAP均低于对照组(P<0.05),且术中丙泊酚和乌拉地尔用量明显低于对照组(P<0.05)。结论在急性脑出血患者术中加用右美托咪定,能保持血流动力学稳定,降低麻醉手术期间的应激反应,减少丙泊酚和乌拉地尔用量,有利于患者恢复,值得临床推广应用。
Objective To observe the application effects of dexmedetomidine in the operative treatment of acute cerebral hemorrhage. MeAods A total of 80 patients with acute cerebral hemorrhage admitted to our hospital for operative treatment were randomly divided into a control group and an experiment group（n=40, respectively）. Conventional general anesthesia was applied to the control group, and on the basis of this, dexmedetomidine was additionally applied to the experiment group. The heart rate （HR） and mean arterial pressure （MAP） during spontaneous breathing with catheter before anesthesia, after anesthesia induction, five minutes after trachea cannula, 60 minutes during the operation and at the end of the operation in the two groups were observed and the amount of propofol and urapidil hydrochloride during operation between the two groups was compared. R抹ults The HR and MAP during spontaneous breathing with catheter after anesthesia induction, five minutes after trachea cannula, 60 minutes during the operation and at the end of the operation were lower than those in the control group （P 〈 0.05）, and the amount of propofol and urapidil hydrochloride during operation was significantly less than that in the control group （P 〈 0.05）. Conclusion The addition of dexmedetomidine during operation on patients with acute cerebral hemorrhage can maintain hemodynamic stability, reduce the stress response during anesthesia as well as the amount of propofol and urapidil hydrochloride, and is beneficial to recovery and worthy of clinical popularization and application.
出处
《西南国防医药》
CAS
2017年第8期814-816,共3页
Medical Journal of National Defending Forces in Southwest China
