摘要
目的：研究右美托咪定在 ICU 无创通气（NPPV）中的临床应用价值。方法选取2013年6月～2014年9月期间由各种原因导致呼吸衰竭而入住我院重症医学科的患者58例，按患者行 NPPV 且未使用右美托咪定时为对照组，用右美托咪定后为观察组。对比两组患者的 Riker 镇静、躁动评分（SAS）、平均动脉压、心率、呼吸频率、血气指标、对 NPPV 的依从性及咳痰能力等。结果使用右美托咪定后的观察组 SAS 评分明显下降，平均动脉压、心率、呼吸频率、血气指标等指标较用药前有明显改善，观察组对 NPPV 的依从性明显增强，P 均＜0.05。结论 ICU 中呼吸衰竭的患者实施 NPPV 时使用右美托咪定能够起到很好的镇静效果，有利于临床治疗及患者病情的恢复，且副作用很小，值得在临床推广。
Objective To study he clinical application value of dexmedetomidine on ICU noninvasive ventilation （NPPV）. Methods 58 cases of patients with respiratory failure were selected in severe medical department of our hospital from June 2013 to September 2014, allocated into 2 groups, the control group received NPPV and without dexmedetomidine, the observation group received NPPV with dexmedetomidine. The Riker sedation agitation scale （SAS）, mean arterial pressure, heart rate, respiratory frequency, blood gas index, the NPPV compliance and sputum ability etc. between the two groups were compared. Results After using of dexmedetomidine, the SAS score decreased significantly, mean arterial pressure, heart rate, respiratory frequency, blood gas index and other indicators in the observation group had improved significantly than that before treatment, NPPV compliance of the observation group was significantly enhanced, P 〈 0.05. Conclusion The use of dexmedetomidine can play a very good sedative effect of respiratory failure in patients with the implementation of NPPV in ICU, which is helpful for clinical treatment and patients in the recovery of the disease, and the side effect is small, is worth in clinical promotion.
出处
《中国医药科学》
2015年第10期171-172,175,共3页
China Medicine And Pharmacy
关键词
右美托咪定
ICU
无创通气
呼吸衰竭
Dexmedetomidine
ICU
Noninvasive ventilation
Respiratory failure
