摘要
目的:观察小柴胡汤联合西药治疗亚急性甲状腺炎(SAT)的临床疗效。方法:选择2017年5月至2019年1月在门诊和住院部就诊的SAT患者80例,按入院顺序进行1:1分为两组,每组40例,西医组采用抗炎镇痛疗法治疗,中西药组则需加用小柴胡汤剂治疗。比较两组甲状腺功能生化指标水平,并记录两组患者临床治疗效果。结果:80例患者治疗后FT3、FT4及TSH均显著改善,与治疗前相比差异具有统计学意义(P<0.01),此外,治疗一个疗程后两组甲状腺功能指标相比,中西药组效果则更优(P<0.01),且中西药组患者甲状腺恢复正常率更高(P<0.01)。西医组治愈患者5例,治疗有效率75%,中西药组治愈患者10例,治疗有效率94%,两组治疗效果相比,差异显著(P<0.05)。结论:小柴胡汤联合西药治疗可有效提高SAT患者甲状腺功能,临床症状改善显著,值得临床推广。
Objective: To observe the clinical effect of Xiaochaihu decoction combined with western medicine on subacute thyroiditis(SAT). Methods: Eighty SAT patients recruited from May 2017 to January 2019, which were visited in clinics and inpatient departments, were randomly divided into two groups, 40 cases in each group. Western medicine group was treated with diclofenac sodium double-release enteric-coated capsule orally, while western medicine group was treated with Xiaochaihu decoction on the basis of Western medicine group. The biochemical indexes of thyroid function were compared between the two groups, and the clinical effects of the two groups were recorded. Results: FT3,FT4 and TSH of 80 patients were significantly improved after treatment, and the difference was statistically significant compared with before treatment(P<0.01). In addition, after treatment, the two groups of thyroid function indicators, the thyroid function indicators of the Chinese and Western medicine group was significantly better than the Western medicine group after treatment, and the rate of thyroid return to normal was higher in the treatment group(P<0.01). Five patients were cured in the western medicine group, the effective rate is 75%. Ten patients were cured in the Chinese and Western medicine group, the effective rate is 94%, there was a significant difference between the two groups(P<0.05).Conclusion: Xiaochaihu Decoction combined with western medicine can effectively improve the thyroid function of patients,the clinical symptoms were improved significantly, so it is worthy of clinical promotion.
作者
凌俊辉
马妮
曾烨
LING Junhui;MA Ni;ZENG Ye(Guangdong Meizhou Hospital of Traditional Chinese Medicine (Tianjiabing Hospital), Guangdong Meizhou 514000, China)
出处
《中医药临床杂志》
2019年第8期1537-1539,共3页
Clinical Journal of Traditional Chinese Medicine
关键词
小柴胡汤
西药治疗
急性期亚急性甲状腺炎
临床疗效
Xiaochaihu decoction
Prescription addition and subtraction
Acute subacute thyroiditis
Comprehensive curative effect of TCM syndromes