摘要
目的探讨鼻腔扩容术治疗伴有鼻塞症状的睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)成年患者的疗效.方法选取2017年1月至2018年1月于安徽医科大学附属省立医院耳鼻咽喉头颈外科住院的伴有鼻塞症状的OSAHS患者32例,男28例,女4例,年龄(40.3±8.5)岁((x)±s,下同),实施个体化的鼻腔扩容术.术前和术后3个月分别进行鼻声反射和鼻阻力检查、多导睡眠监测(polysomnography,PSG),并填写鼻阻塞症状评估量表(nasal obstruction symptom evaluation,NOSE)及魁北克睡眠问卷(Quebec sleep questionnaire,QSQ).对比分析手术前后患者的鼻声反射、鼻阻力、NOSE、QSQ量表分值、呼吸暂停低通气指数(apnea hypopnea index,AHI)、最低动脉血氧饱和度(lowest arterial oxygen saturation,LSaO2)等.使用SPSS 20.0软件进行统计学分析.结果患者术后的鼻腔总阻力较术前明显下降,NOSE量表总分显著降低,QSQ量表总分显著提高[(0.140±0.043) kPa· s/L比(0.277±0.067) kPa· s/L,(9.84±4.11)分比(53.00±11.57)分,(5.67±0.43)分比(3.86±0.46)分,t值分别为10.687、18.035、-16.904,P值均<0.05],其5个维度评分均有不同程度的提高.在PSG各指标中,术后AHI较术前有下降趋势,LSaO2较术前有所提高,但差异无统计学意义.结论鼻腔扩容术可以有效缓解OSAHS患者的鼻塞症状,改善患者的睡眠及生活质量.
Objective To investigate the effect of nasal cavity ventilation expansion techniques in treatment of obstructive sleep apnea hypopnea syndrome (OSAHS) with nasal obstruction. Methods Thirty-two OSAHS patients with nasal obstruction hospitalized from January 2017 to January 2018 in Department of Otorhinolaryngology Head and Neck Surgery, Provincial Hospital Affiliated to Anhui Medical University were selected, with 28 males and 4 females, aged 40.3±8.5 years old (±s), and treated with individualized nasal cavity ventilation expansion techniques. Nasal acoustic reflex and resistance examination, polysomnography (PSG) monitoring were performed before and three months after operation. Nasal obstruction symptom evaluation (NOSE) and Quebec sleep questionnaire (QSQ) were completed as well. The nasal acoustic reflex, nasal resistance, NOSE, QSQ score, apnea hypopnea index (AHI) and lowest arterial oxygen saturation (LSaO2) before and after operation were compared and analyzed. SPSS 22.0 software was used for statistical analysis. Results After the operation, the total nasal resistance and total score of NOSE scale of patients decreased significantly as well as the total score of QSQ scale increased significantly ((0.140±0.043) kPa·s/L vs (0.277±0.067) kPa·s/L, 9.84±4.11 vs 53.00±11.57, 5.67±0.43 vs 3.86±0.46, t value was 10.687, 18.035,-16.904, respectively, all P<0.05), and the scores of five dimensions increased in varying degrees. Among the indexes of PSG, there was no significant difference in AHI and LSaO2 values before and after operation, but AHI decreased and LSaO2 increased. Conclusion Nasal cavity ventilation expansion techniques can effectively alleviate the symptoms of nasal obstruction in OSAHS patients and improve their sleep and quality of life.
作者
周宜存
孙敬武
Zhou Yicun;Sun Jingwu(Department of Otorhinolaryngology Head and Neck Surgery,Provincial Hospital Affiliated toAnhui Medical University,First Affiliated Hospital of University of Science and Technology of China,Hefei 230001,China;Department of Otorhinolaryngology,Head and Neck Surgery,Lu'an Second People's Hospital,Lu'an 237000,China)
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2019年第8期606-609,共4页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
关键词
鼻腔扩容术
睡眠呼吸暂停
阻塞性
鼻塞
Nasal cavity ventilation expansion techniques
Sleep apnea,obstructive
Nasal obstruction
